{"id":"W2080963472","doi":"10.1161/circresaha.107.148676","title":"Therapeutic Arteriogenesis by Ultrasound-Mediated VEGF <sub>165</sub> Plasmid Gene Delivery to Chronically Ischemic Skeletal Muscle","year":2007,"lang":"en","type":"article","venue":"Circulation Research","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":165,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Arteriogenesis; Microbubbles; Medicine; Vascular endothelial growth factor; Perfusion; Ischemia; Gene delivery; Angiogenesis; Skeletal muscle; Genetic enhancement; Neovascularization; Ultrasound; Pathology; Cardiology; Internal medicine; Biology; Gene; Radiology; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006996178,0.000195248,0.0001784286,0.0002668909,0.0002663589,0.0001088426,0.0003000495,0.0001971276,0.0001592011],"category_scores_gemma":[0.00008043088,0.0002157013,0.0000866934,0.0009087996,0.0001046653,0.0001469144,0.00003102566,0.0003478708,0.0009859349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003129724,"about_ca_system_score_gemma":0.00008106475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002944624,"about_ca_topic_score_gemma":0.00007613978,"domain_scores_codex":[0.9978784,0.00005582991,0.0003532471,0.0003815003,0.0006050622,0.0007259965],"domain_scores_gemma":[0.9983828,0.0006321258,0.00002558563,0.0004348818,0.0002227175,0.0003018987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006618573,0.00005645606,0.0009431212,0.00002284652,0.00004774016,0.00000233702,0.0001745021,0.002806935,0.9812663,0.00002058284,0.002455729,0.01219685],"study_design_scores_gemma":[0.001011956,0.00009382527,0.3165501,0.00004157783,0.00003900399,0.0000365856,0.0002219146,0.009354458,0.5954002,0.0001412249,0.07624308,0.0008661327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984356,0.0008441546,0.0124939,0.0001699611,0.00008184328,0.0004899115,0.00005160377,0.000294409,0.001218142],"genre_scores_gemma":[0.9987656,0.0002492379,0.0001623591,0.0001407716,0.0001932612,0.0001210794,0.0002491486,0.00007756882,0.00004092552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3858661,"threshold_uncertainty_score":0.9997919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0215011844602051,"score_gpt":0.2734383130052008,"score_spread":0.2519371285449957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}