{"id":"W2080973779","doi":"10.1126/sageke.2004.31.re5","title":"Murine Models of Life Span Extension","year":2004,"lang":"en","type":"review","venue":"Science of Aging Knowledge Environment","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Dwarfism; Longevity; Biology; Life span; Mutant; Phenotype; Growth hormone receptor; Mutation; Endocrinology; Receptor; Cell biology; Genetics; Internal medicine; Growth hormone; Hormone; Gene; Evolutionary biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000624913,0.000379969,0.0008592542,0.0002023986,0.0001025223,0.00001488199,0.000848788,0.0001976633,0.0000258696],"category_scores_gemma":[0.00005232058,0.0003371256,0.0003089161,0.0001909189,0.001037679,0.000008490158,0.0007284156,0.0001571377,0.00002751849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000106464,"about_ca_system_score_gemma":0.0007702124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001298392,"about_ca_topic_score_gemma":0.000001843344,"domain_scores_codex":[0.9976602,0.00006194204,0.0006477262,0.0008195429,0.0004154342,0.0003951254],"domain_scores_gemma":[0.9982436,0.00001180894,0.0004593756,0.001030664,0.00005622792,0.0001982817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002137561,0.002357559,0.00006144219,0.04219007,0.0004364787,0.000009836418,0.003050617,0.0338883,0.07187848,0.0008608149,0.0003483025,0.8448967],"study_design_scores_gemma":[0.001972527,0.001916876,0.0002466002,0.02429978,0.001786718,0.00009129891,0.0003144793,0.00162732,0.1451844,0.002151314,0.8166289,0.003779785],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002801394,0.9917881,0.004242797,0.00001001556,0.0002725115,0.0003712806,0.0000181053,0.000007371615,0.0004883527],"genre_scores_gemma":[0.0529974,0.9433484,0.003083824,0.00000763784,0.0001250563,0.00001283699,0.00003315803,0.00004550397,0.0003461746],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.841117,"threshold_uncertainty_score":0.9999081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0317561691344971,"score_gpt":0.2818251898052948,"score_spread":0.2500690206707977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}