{"id":"W2080985963","doi":"10.1529/biophysj.107.116897","title":"Analysis of Serial Engagement and Peptide-MHC Transport in T Cell Receptor Microclusters","year":2008,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"T-cell receptor; Major histocompatibility complex; CD8; Biophysics; Cluster (spacecraft); Antigen; T cell; Biology; Immunology; Immune system; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000200068,0.0001686372,0.0005229824,0.0003114461,0.0001623851,0.000004995767,0.000182417,0.000182847,0.0004636383],"category_scores_gemma":[0.000007914073,0.000140971,0.0002399792,0.0003537924,0.000359521,0.00007189186,0.00004681979,0.0005144255,0.00005666858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003346892,"about_ca_system_score_gemma":0.00005264023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008842587,"about_ca_topic_score_gemma":0.00001763431,"domain_scores_codex":[0.9987175,0.0002267104,0.0004656196,0.0002277907,0.00004734463,0.0003150423],"domain_scores_gemma":[0.9995168,0.00007352517,0.0001829236,0.0001420037,0.00004780852,0.00003697993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003606536,0.0004440302,0.009733261,0.000009348028,0.0005688023,0.00003189409,0.001207482,0.00003418917,0.9868712,0.00001782622,0.0003996475,0.0003216903],"study_design_scores_gemma":[0.002986767,0.0004408651,0.03291677,0.00001755468,0.0004731903,0.0001160571,0.0004506477,0.00001217998,0.9572161,0.000007743577,0.005119489,0.0002425799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987445,0.0003168177,0.00006443347,0.000116025,0.0004039019,0.00008096935,0.00002361536,0.00001097688,0.0002387979],"genre_scores_gemma":[0.9983607,0.0005245655,0.0001164949,0.00006064255,0.00005912731,0.000002760907,0.00004070481,0.000009726546,0.0008252904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02965502,"threshold_uncertainty_score":0.5748631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01390355151233162,"score_gpt":0.2164937787529316,"score_spread":0.2025902272406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}