{"id":"W2080987339","doi":"10.1006/excr.2001.5297","title":"A Verotoxin 1 B Subunit-Lambda CRO Chimeric Protein Specifically Binds Both DNA and Globotriaosylceramide (Gb3) to Effect Nuclear Targeting of Exogenous DNA in Gb3 Positive Cells","year":2001,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children; Institute of Infection and Immunity","funders":"","keywords":"Biology; Molecular biology; Golgi apparatus; Biochemistry; DNA; Endoplasmic reticulum; Dynactin; Protein subunit; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000331759,0.0004636454,0.0003836007,0.0003838037,0.0003193034,0.0004920972,0.0003722095,0.0005108597,0.0016343],"category_scores_gemma":[0.0002247611,0.0003650966,0.0003972902,0.0002817524,0.0005698351,0.0003668918,0.0003890612,0.001118368,0.0007050316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005291473,"about_ca_system_score_gemma":0.0003796483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001612935,"about_ca_topic_score_gemma":0.002128872,"domain_scores_codex":[0.9996568,0.00005672567,0.00002573719,0.00008073507,0.00008109282,0.00009897559],"domain_scores_gemma":[0.9996141,0.0001384276,0.00007032839,0.00006807705,0.00002288242,0.00008622339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003737841,0.0000058891,0.00002389359,0.000008093814,0.000001119416,0.0000142807,0.000008557941,0.00001430138,0.9996784,0.00009232991,0.000005252325,0.0001106247],"study_design_scores_gemma":[0.00001104096,0.00007855552,0.0004896866,0.000002266633,0.00000558412,0.00006807088,0.000009995571,0.0002399974,0.9984469,0.00002272218,0.0006235152,0.00000167756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855044,0.0008341709,0.01023084,0.0001424623,0.0000554882,0.00005548772,0.0002707803,0.0002292612,0.002677093],"genre_scores_gemma":[0.9881067,0.0003947969,0.004706529,0.00004304278,0.00001300157,0.00003392492,0.0006355978,0.00009306298,0.005973477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0016343,"threshold_uncertainty_score":0.005467296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01958031658522669,"score_gpt":0.3088059259530972,"score_spread":0.2892256093678706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}