{"id":"W2080989966","doi":"10.1016/j.jconrel.2011.05.020","title":"Optimization of a novel and improved thermosensitive liposome formulated with DPPC and a Brij surfactant using a robust in vitro system","year":2011,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":154,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Liposome; Pulmonary surfactant; In vitro; Chemistry; Biophysics; Chromatography; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005269691,0.0004021598,0.0002949847,0.0001937378,0.0001868969,0.0004909959,0.0002709523,0.0004126569,0.0005893849],"category_scores_gemma":[0.0002316758,0.0002590081,0.0003067887,0.0001231729,0.0002387768,0.0004474027,0.000310177,0.0004320492,0.0004277835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004468043,"about_ca_system_score_gemma":0.0002734955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005251432,"about_ca_topic_score_gemma":0.0008315096,"domain_scores_codex":[0.9997911,0.00003257798,0.00003451325,0.00005441588,0.00006243948,0.00002493934],"domain_scores_gemma":[0.9998978,0.0000143792,0.00003529776,0.000009021558,0.00002866996,0.00001477005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004175857,0.00001529737,0.00003221219,0.00002273702,0.000003116658,0.00001309789,0.000007709303,0.0001258622,0.999184,0.00005442195,0.00001530867,0.000484419],"study_design_scores_gemma":[0.000007581376,0.00004234234,0.0000913241,0.000001485488,0.000007961081,0.00001410508,0.000003315838,0.0008081906,0.9984755,0.000005219382,0.0005394878,0.000003440942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9633812,0.001458136,0.03310411,0.0001989833,0.00007331365,0.0001524718,0.0003045337,0.0001761093,0.001151142],"genre_scores_gemma":[0.9734076,0.0008970507,0.02215539,0.00008384297,0.00001634872,0.0001203287,0.0004145182,0.00008054668,0.00282436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005893849,"threshold_uncertainty_score":0.003241837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01650199258722873,"score_gpt":0.2007008428625727,"score_spread":0.184198850275344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}