{"id":"W2080991292","doi":"10.1002/art.30150","title":"A distinct role for transient receptor potential ankyrin 1, in addition to transient receptor potential vanilloid 1, in tumor necrosis factor α-induced inflammatory hyperalgesia and Freund's complete adjuvant-induced monarthritis","year":2010,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":168,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Biotechnology and Biological Sciences Research Council; Versus Arthritis","keywords":"TRPV1; Hyperalgesia; Transient receptor potential channel; Freund's adjuvant; Pharmacology; Medicine; Tumor necrosis factor alpha; Antagonist; Receptor antagonist; Inflammation; Receptor; Endocrinology; Nociception; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002253446,0.0005838361,0.0006210041,0.0005177618,0.0001939021,0.0004101991,0.0003252811,0.0008263994,0.001434981],"category_scores_gemma":[0.0002749046,0.0002656329,0.0005743735,0.0001763008,0.0003825376,0.0006769645,0.0003651516,0.0009588164,0.0003122973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003159946,"about_ca_system_score_gemma":0.0002447778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002093,"about_ca_topic_score_gemma":0.0002893473,"domain_scores_codex":[0.9997386,0.00002490288,0.00002563946,0.0000648704,0.00005798936,0.0000879566],"domain_scores_gemma":[0.9996132,0.0000309019,0.0002125866,0.00002851713,0.00003057919,0.00008415194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002321482,0.00001912509,0.0001555938,0.00009943747,0.000005786708,0.0001577213,0.00001075049,0.00002507657,0.9986591,0.00005865015,0.00001155785,0.0005650441],"study_design_scores_gemma":[0.0001842357,0.00277743,0.08523841,0.0001060298,0.000165988,0.006759049,0.0001709834,0.001169313,0.9001347,0.0003933205,0.002865036,0.00003551713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98725,0.008420174,0.003065541,0.0001509662,0.00004940146,0.00004417626,0.0002880319,0.00008041178,0.0006512625],"genre_scores_gemma":[0.9921909,0.002419936,0.002359079,0.00007835308,0.00003656671,0.00007847377,0.000382073,0.00001358952,0.002441135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001434981,"threshold_uncertainty_score":0.004800498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01419147728143328,"score_gpt":0.2248162871445257,"score_spread":0.2106248098630924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}