{"id":"W2081016717","doi":"10.1016/j.jaad.2009.09.014","title":"Ustekinumab significantly improves symptoms of anxiety, depression, and skin-related quality of life in patients with moderate-to-severe psoriasis: Results from a randomized, double-blind, placebo-controlled phase III trial","year":2010,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":216,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Ustekinumab; Dermatology Life Quality Index; Psoriasis; Anxiety; Quality of life (healthcare); Placebo; Depression (economics); Hospital Anxiety and Depression Scale; Randomized controlled trial; Internal medicine; Physical therapy; Dermatology; Psychiatry; Disease; Alternative medicine; Pathology; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001057592,0.0003271757,0.003485925,0.0003617405,0.00007602089,0.000007015818,0.0005359559,0.0004223322,0.00001844526],"category_scores_gemma":[0.0007169544,0.0001886169,0.0004245224,0.0003413384,0.0009793825,0.0001341092,0.0001179038,0.0007439135,0.000001292551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001913791,"about_ca_system_score_gemma":0.0002256901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004411334,"about_ca_topic_score_gemma":0.00003579219,"domain_scores_codex":[0.9945946,0.001750591,0.002835736,0.0003223344,0.0001830762,0.0003136837],"domain_scores_gemma":[0.9915779,0.001777128,0.006070162,0.0002800958,0.0002068481,0.00008785703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9509975,0.000968417,0.01055244,0.00001543601,0.00270592,0.000001530113,0.0009210005,0.00004016406,0.02958248,0.000037744,0.00006792932,0.004109496],"study_design_scores_gemma":[0.9558956,0.0006872082,0.01472092,0.00008513663,0.000908873,0.00005532368,0.0002261887,0.00001621474,0.02707097,0.0001278977,0.00001668549,0.0001889911],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965544,0.0005676369,0.00001709202,0.0005303343,0.0004051221,0.001724305,0.0001569957,0.000006956247,0.00003711738],"genre_scores_gemma":[0.9994735,0.0001248276,0.0001830644,0.00008751502,0.0000326549,0.00004170123,0.00001678338,0.00001938799,0.0000205964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004898142,"threshold_uncertainty_score":0.7691573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0137775545181885,"score_gpt":0.2760983433877126,"score_spread":0.2623207888695241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}