{"id":"W2081106264","doi":"10.1091/mbc.11.8.2605","title":"The Yeast<i>TEL1</i>Gene Partially Substitutes for Human<i>ATM</i>in Suppressing Hyperrecombination, Radiation-Induced Apoptosis and Telomere Shortening in A-T Cells","year":2000,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute; National Institutes of Health","keywords":"Biology; Ataxia-telangiectasia; Complementation; Saccharomyces cerevisiae; Telomere; Gene; Mutant; Phenotype; Mutation; Cell biology; Genetics; Yeast; Apoptosis; Molecular biology; DNA damage; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008738409,0.0003314445,0.000151551,0.000246362,0.0001464817,0.0003218922,0.0002240753,0.0001824111,0.001230606],"category_scores_gemma":[0.0001083076,0.0001400671,0.000162628,0.0001912133,0.0002444751,0.0001444027,0.0001686725,0.0002969599,0.0006544605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002339265,"about_ca_system_score_gemma":0.0002281816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005304319,"about_ca_topic_score_gemma":0.000575356,"domain_scores_codex":[0.9999254,0.00001380732,0.000009325133,0.00001538546,0.00001711271,0.00001899849],"domain_scores_gemma":[0.9998684,0.00002392043,0.00004338491,0.00001722597,0.000008966534,0.00003807662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001021723,0.00001744379,0.0001677112,0.00001692885,0.000003100942,0.00006706444,0.000006141113,0.00009372626,0.9984972,0.000150105,0.00002331209,0.0008551389],"study_design_scores_gemma":[0.0000267388,0.0001837593,0.002611635,0.000006103381,0.00001580809,0.0008444558,0.0000234635,0.0008802516,0.992702,0.00007324681,0.002628848,0.000003644495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964162,0.0006978251,0.001568593,0.00004770535,0.00000932536,0.00001051307,0.0002109294,0.0001024487,0.0009364824],"genre_scores_gemma":[0.9961056,0.0003622239,0.001290033,0.00001732174,0.000004526405,0.00001019214,0.0006390978,0.00003197418,0.001539057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001230606,"threshold_uncertainty_score":0.004116774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00675480046275732,"score_gpt":0.2375540895357197,"score_spread":0.2307992890729624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}