{"id":"W2081120465","doi":"10.1016/j.vaccine.2007.04.085","title":"Immunogenicity and in vitro protective efficacy of a polyepitope Plasmodium falciparum candidate vaccine constructed by epitope shuffling","year":2007,"lang":"en","type":"article","venue":"Vaccine","topic":"Malaria Research and Control","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute for Basic Science; University of Toronto","keywords":"Epitope; Immunogenicity; Plasmodium falciparum; Biology; Antigen; Virology; Reverse vaccinology; Malaria vaccine; Adjuvant; Antibody; Malaria; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007941111,0.0002469128,0.0007210388,0.0003578577,0.00006963788,0.00001700201,0.0001456273,0.0001550446,0.0001452001],"category_scores_gemma":[0.000616264,0.0002069258,0.00008232977,0.0005379916,0.0000275799,0.00009185618,0.0001133377,0.0005166703,0.000005733857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001071617,"about_ca_system_score_gemma":0.0001631112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002190969,"about_ca_topic_score_gemma":0.0003151239,"domain_scores_codex":[0.9978955,0.00008828233,0.0006341591,0.000406875,0.0003155206,0.0006596191],"domain_scores_gemma":[0.9987311,0.0002666656,0.000167465,0.0003624813,0.0001820424,0.000290289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02768994,0.0002948806,0.02085629,0.00009628967,0.0001868082,0.00009109195,0.0001446296,0.000001865019,0.9359756,0.0000584996,0.0001404728,0.01446369],"study_design_scores_gemma":[0.02563023,0.0006641073,0.311195,0.0001326138,0.0000849837,0.0001114868,0.0001561322,0.0006956979,0.6606808,0.00006406959,0.0003640514,0.0002207734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931917,0.002319423,0.0006725685,0.001845971,0.0000685675,0.001576182,0.00005840039,0.00004372696,0.0002234545],"genre_scores_gemma":[0.9990281,0.0001414379,0.0004058323,0.0001209083,0.0000984031,0.00003448511,0.00005017061,0.00002770825,0.0000929548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2903387,"threshold_uncertainty_score":0.8438188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007689795896923731,"score_gpt":0.2650428399130686,"score_spread":0.2573530440161448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}