{"id":"W2081120465","doi":"10.1016/j.vaccine.2007.04.085","title":"Immunogenicity and in vitro protective efficacy of a polyepitope Plasmodium falciparum candidate vaccine constructed by epitope shuffling","year":2007,"lang":"en","type":"article","venue":"Vaccine","topic":"Malaria Research and Control","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute for Basic Science; University of Toronto","keywords":"Epitope; Immunogenicity; Plasmodium falciparum; Biology; Antigen; Virology; Reverse vaccinology; Malaria vaccine; Adjuvant; Antibody; Malaria; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002742093,0.0004071681,0.0001979308,0.0001867525,0.000143544,0.0002222839,0.0001908987,0.000271105,0.001018061],"category_scores_gemma":[0.0003106223,0.0001797966,0.0002165484,0.0001496765,0.0001935021,0.0002218401,0.000153199,0.0008213671,0.0002343216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002108776,"about_ca_system_score_gemma":0.0001801637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004997615,"about_ca_topic_score_gemma":0.0003396934,"domain_scores_codex":[0.9998412,0.00004579444,0.00001524301,0.00001966931,0.00002647039,0.00005156906],"domain_scores_gemma":[0.9998109,0.00007297422,0.00003461229,0.00002111433,0.0000273259,0.00003317584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001218742,0.0003232202,0.0005478629,0.00003644549,0.00001161805,0.000068897,0.0000215125,0.0007102867,0.995607,0.0001147894,0.00005686337,0.001282738],"study_design_scores_gemma":[0.0001226007,0.00388601,0.003713201,0.0000050205,0.00004322033,0.0002492316,0.00002897672,0.003332979,0.9880449,0.00006878305,0.0004994412,0.000005594799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988773,0.0001553047,0.0005689637,0.00002141553,0.00001271753,0.00001239065,0.0001018615,0.000006819833,0.0002431506],"genre_scores_gemma":[0.9984025,0.0001135959,0.0003840067,0.00002023503,0.000007920139,0.00001397399,0.0005083022,0.00000470101,0.0005447901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001018061,"threshold_uncertainty_score":0.00340569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007689795896923731,"score_gpt":0.2650428399130686,"score_spread":0.2573530440161448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}