{"id":"W2081128157","doi":"10.1182/blood-2006-04-018341","title":"In vivo tumor growth is inhibited by cytosolic iron deprivation caused by the expression of mitochondrial ferritin","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"McGill University; Mayo Clinic","keywords":"Cytosol; Ferritin; Mitochondrion; Transferrin receptor; Frataxin; Intracellular; Biology; Heme; Cell biology; Aconitase; Transferrin; Chemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001433909,0.0003759646,0.0002879227,0.0002244431,0.0001194289,0.0002235167,0.0001542451,0.0002089074,0.001209295],"category_scores_gemma":[0.0001474039,0.0001360784,0.0001632798,0.0001080749,0.0002041177,0.0001292826,0.0001630271,0.0007167336,0.0003128171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003008288,"about_ca_system_score_gemma":0.0001908558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008548847,"about_ca_topic_score_gemma":0.001036851,"domain_scores_codex":[0.9998825,0.00002703025,0.000007514251,0.00001694794,0.00003229991,0.0000337536],"domain_scores_gemma":[0.999809,0.00005534136,0.00004468633,0.00002279396,0.00001265425,0.00005557169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002210601,0.00006964659,0.00009749716,0.0000124371,0.000003703489,0.00002689218,0.000006884926,0.00004286381,0.9986877,0.00006210911,0.00007694448,0.0006923177],"study_design_scores_gemma":[0.00003115732,0.0006810997,0.00126842,0.000003376731,0.000008882614,0.0001688305,0.00001068389,0.001118697,0.9954649,0.00003844929,0.001203473,0.000002055216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941837,0.001244703,0.002285702,0.0002096669,0.00003589291,0.00001883245,0.0002659771,0.000203034,0.001552484],"genre_scores_gemma":[0.9948601,0.0005372586,0.001348723,0.0000468386,0.00001191202,0.00002633503,0.0006919732,0.00004715403,0.002429816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001209295,"threshold_uncertainty_score":0.004045486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005487020425139519,"score_gpt":0.2202163881238813,"score_spread":0.2147293676987418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}