{"id":"W2081215964","doi":"10.1039/c3mb70493a","title":"Electrochemical detection of the Fc-STAT3 phosphorylation and STAT3–Fc-STAT3 dimerization and inhibition","year":2013,"lang":"en","type":"article","venue":"Molecular BioSystems","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dairy Farmers of Ontario; The Scarborough Hospital; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"STAT protein; STAT3; Chemistry; Ferrocene; Electrochemistry; Redox; Activator (genetics); Phosphorylation; Biophysics; Biochemistry; Cell biology; Combinatorial chemistry; Biology; Receptor; Electrode; Inorganic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001067259,0.0001475177,0.0001634373,0.00003446281,0.00007524745,0.00004153321,0.00006077998,0.0001585173,0.00000961373],"category_scores_gemma":[0.00009161039,0.0001162388,0.00008394298,0.0001618504,0.00008744553,0.000009009033,0.00007031234,0.00006924725,0.000002773138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001733064,"about_ca_system_score_gemma":0.00001464814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001103093,"about_ca_topic_score_gemma":0.00002090937,"domain_scores_codex":[0.9990095,0.00008069498,0.0002651708,0.0003152982,0.0001652555,0.000164024],"domain_scores_gemma":[0.9994456,0.00001279712,0.0001563547,0.000222749,0.00009792419,0.00006459499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001873453,0.00002199254,0.0007024839,0.00004636972,0.00004396007,2.016353e-7,0.00002257836,0.000003246038,0.9968276,0.00002125235,0.00002558954,0.002266001],"study_design_scores_gemma":[0.0002244905,0.00009246196,0.001010133,0.00003157523,0.00004646436,0.000006294818,0.00005101512,0.0008290421,0.9967112,0.00007613695,0.0007811725,0.0001400339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886681,0.001211443,0.009590478,0.0001380968,0.00003235453,0.0002650712,0.00001314753,0.000009822053,0.000071482],"genre_scores_gemma":[0.999438,0.0001613207,0.0001079451,0.00006223396,0.00004261288,0.00003019849,0.00009504063,0.00001901031,0.00004357079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01076996,"threshold_uncertainty_score":0.4740081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.001961044437703284,"score_gpt":0.170856578115171,"score_spread":0.1688955336774678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}