{"id":"W2081291846","doi":"10.1016/j.cellimm.2005.06.004","title":"Strong memory CD8+ T cell responses against immunodominant and three new subdominant HLA-B27-restricted influenza A CTL epitopes following secondary infection of HLA-B27 transgenic mice","year":2005,"lang":"en","type":"article","venue":"Cellular Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Ontario HIV Treatment Network","keywords":"Epitope; Subdominant; CTL*; Biology; Virology; Immunology; CD8; Human leukocyte antigen; Cytotoxic T cell; Genetically modified mouse; Influenza vaccine; Antigen; Transgene; Virus; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0007084365,0.0009343525,0.001612051,0.0007237968,0.0005375592,0.00004342185,0.0008391617,0.0015549,0.0004769265],"category_scores_gemma":[0.0001856118,0.0009049364,0.0006603517,0.0005540872,0.001170127,0.0004115014,0.0004666659,0.001652224,0.0004803368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001962443,"about_ca_system_score_gemma":0.0006422939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002185946,"about_ca_topic_score_gemma":0.0004935319,"domain_scores_codex":[0.9943915,0.001118984,0.001728525,0.001147645,0.0001234094,0.001489928],"domain_scores_gemma":[0.9970491,0.0007251793,0.0008115027,0.001170079,0.0001456522,0.00009850188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002420859,0.0004486896,0.001626753,0.00008684175,0.001112387,0.00005488016,0.001317339,0.00003049677,0.9470467,0.0001716253,0.0003521834,0.04533124],"study_design_scores_gemma":[0.01082023,0.001083006,0.007050829,0.0001285475,0.0004839328,0.0002205397,0.0004818212,0.00002137259,0.9305517,0.0001411345,0.04812089,0.0008960141],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8651956,0.1294896,0.0007107944,0.0002574912,0.002499176,0.0008106339,0.00004607435,0.0002030403,0.0007875758],"genre_scores_gemma":[0.9913523,0.003515525,0.0004179694,0.0001669675,0.0001491319,0.00006088898,0.0002166306,0.00012246,0.003998132],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1261567,"threshold_uncertainty_score":0.9997413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01281136863625171,"score_gpt":0.2245515256999349,"score_spread":0.2117401570636832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}