{"id":"W2081306659","doi":"10.1021/bc0100814","title":"A Simple Two-Step Approach for Introducing a Protected Diaminedithiol Chelator during Solid-Phase Assembly of Peptides","year":2002,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Chemistry; Moiety; Chelation; Lysine; Peptide; Tripeptide; Chinese hamster ovary cell; Residue (chemistry); Amino acid; Combinatorial chemistry; Solid-phase synthesis; Stereochemistry; Peptide synthesis; Ligand (biochemistry); Biochemistry; Organic chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001558167,0.0002842664,0.0003979251,0.00002750579,0.0001029534,0.00003189339,0.000272961,0.0002335574,0.00008877796],"category_scores_gemma":[0.0004002221,0.0002682034,0.0003236973,0.0001503761,0.0001045615,0.000006889509,0.0001219035,0.0001149388,0.000002465269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002869996,"about_ca_system_score_gemma":0.00002324591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001386253,"about_ca_topic_score_gemma":0.000001024371,"domain_scores_codex":[0.9983096,0.00002003425,0.0004649072,0.0006551773,0.0001571343,0.0003931427],"domain_scores_gemma":[0.9988957,0.00002381791,0.0002526011,0.0005271815,0.000148466,0.0001522399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000106747,0.0003465557,0.0001186857,0.0004613697,0.000184749,0.000001133396,0.00002135605,0.00003473397,0.9973801,0.000001595855,0.0006571033,0.0006859077],"study_design_scores_gemma":[0.001920857,0.00006940103,0.00002205569,0.00002670772,0.00008654616,0.000009711564,0.00007476765,0.005077965,0.9906949,0.000005410633,0.001685613,0.0003260149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956492,0.0004490784,0.00271921,0.00005049071,0.00001639635,0.0003863724,0.0001198117,0.00003070925,0.0005787163],"genre_scores_gemma":[0.9943711,0.00004895408,0.003414391,0.00002913493,0.0008128171,0.0002483407,0.0003157854,0.00004532489,0.000714217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006685113,"threshold_uncertainty_score":0.999977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01255099319259018,"score_gpt":0.2698195971133426,"score_spread":0.2572686039207524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}