{"id":"W2081365397","doi":"10.1097/ftd.0b013e31823cdec9","title":"The Role of Therapeutic Drug Monitoring of Imatinib in Patients with Chronic Myeloid Leukemia and Metastatic or Unresectable Gastrointestinal Stromal Tumors","year":2011,"lang":"en","type":"review","venue":"Therapeutic Drug Monitoring","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Burnaby Hospital; University of British Columbia","funders":"","keywords":"Imatinib; Medicine; GiST; Myeloid leukemia; Imatinib mesylate; Tyrosine-kinase inhibitor; Internal medicine; Therapeutic drug monitoring; Oncology; Chronic myelogenous leukemia; Adverse effect; Pharmacology; Pharmacokinetics; Gastroenterology; Leukemia; Cancer; Stromal cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003071108,0.0004575872,0.0007920163,0.000847769,0.0003351338,0.001607894,0.0004961958,0.0008500808,0.0008871091],"category_scores_gemma":[0.01133467,0.0001453322,0.0005468623,0.0009212444,0.0003613748,0.001262819,0.0005747815,0.001006928,0.0003079479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006292696,"about_ca_system_score_gemma":0.0007673146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008716842,"about_ca_topic_score_gemma":0.001168769,"domain_scores_codex":[0.9978198,0.001091899,0.0003311749,0.0002600728,0.0004164932,0.00008063376],"domain_scores_gemma":[0.9939939,0.002969251,0.001330354,0.0001825967,0.00100404,0.0005198915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001856378,0.0001872042,0.4799567,0.0004231523,0.0002380869,0.0012454,0.000297323,0.002806372,0.002556939,0.001328179,0.004344862,0.5047594],"study_design_scores_gemma":[0.0005823586,0.004010885,0.7856656,0.00225844,0.001288728,0.01571875,0.001044115,0.09283417,0.01263003,0.009143714,0.07458776,0.0002355422],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.7679971,0.1304852,0.03094237,0.02398482,0.001080165,0.0003314092,0.0007419199,0.0005067383,0.04393031],"genre_scores_gemma":[0.9753991,0.006308505,0.01587924,0.001159451,0.0004426546,0.00005111063,0.0001942297,0.00002192339,0.0005437221],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.003071108,"threshold_uncertainty_score":0.01624179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03223681275316437,"score_gpt":0.2984405817522909,"score_spread":0.2662037689991266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}