{"id":"W2081406702","doi":"10.1038/modpathol.2012.95","title":"Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples","year":2012,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"National Cancer Institute; Cancer Research UK; Jerry M. Lewis, M.D. Mental Health Research Foundation","keywords":"Apoptosis; Colorectal cancer; Cancer cell; Programmed cell death; Cancer; Ovarian cancer; Biology; Cancer research; Melanoma; Necroptosis; Caspase 3; Tropism; microRNA; Molecular biology; Virology; Pathology; Medicine; Virus; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004178618,0.0002405442,0.0004629126,0.0008719937,0.0003407141,0.0009276854,0.0002573124,0.0005229668,0.001824935],"category_scores_gemma":[0.0016364,0.0002135012,0.0002829884,0.0006752461,0.0003879073,0.0002057112,0.0002659091,0.0006228882,0.0005594613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000299008,"about_ca_system_score_gemma":0.0002157152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005074958,"about_ca_topic_score_gemma":0.0005381771,"domain_scores_codex":[0.9991297,0.00014464,0.0001051215,0.0001857078,0.0002869799,0.0001479121],"domain_scores_gemma":[0.9991772,0.0002023228,0.0002553788,0.00008950092,0.0001938047,0.00008183356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004080101,0.0002024376,0.242049,0.0002801299,0.0002004503,0.001294352,0.0003561372,0.0001879737,0.7343318,0.000251254,0.0005826549,0.01618368],"study_design_scores_gemma":[0.00005104049,0.001142849,0.5232614,0.00003977935,0.000224708,0.008087395,0.0005847646,0.001830568,0.4602138,0.0003343917,0.004195617,0.0000336254],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949778,0.001956647,0.001202615,0.00008005864,0.00005719563,0.00002298536,0.0005272519,0.00005991782,0.0011157],"genre_scores_gemma":[0.9976612,0.0003085257,0.0008815094,0.00005374868,0.00001485781,0.00002272228,0.0005788351,0.0000157482,0.0004627376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001824935,"threshold_uncertainty_score":0.006105065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07053337819889587,"score_gpt":0.3905661236303832,"score_spread":0.3200327454314874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}