{"id":"W2081406702","doi":"10.1038/modpathol.2012.95","title":"Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples","year":2012,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"National Cancer Institute; Cancer Research UK; Jerry M. Lewis, M.D. Mental Health Research Foundation","keywords":"Apoptosis; Colorectal cancer; Cancer cell; Programmed cell death; Cancer; Ovarian cancer; Biology; Cancer research; Melanoma; Necroptosis; Caspase 3; Tropism; microRNA; Molecular biology; Virology; Pathology; Medicine; Virus; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002065134,0.0001258593,0.0006762692,0.0001505815,0.00002890867,0.000001380382,0.000146235,0.0002539329,0.0001098933],"category_scores_gemma":[0.001092147,0.0000931763,0.0001430728,0.0001765405,0.0002242657,0.00003888638,0.00009607602,0.0004286453,0.00002125902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009337036,"about_ca_system_score_gemma":0.00007961052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002094064,"about_ca_topic_score_gemma":0.0002336485,"domain_scores_codex":[0.9971502,0.001027092,0.0008709162,0.0002611691,0.0001453132,0.0005452696],"domain_scores_gemma":[0.9989868,0.000118046,0.0002456698,0.0003531294,0.0001209528,0.0001754387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000814788,0.0004199991,0.6526511,0.00003489857,0.00007955084,0.00001616154,0.0009305888,0.00003415572,0.3392217,0.00002831644,0.001163923,0.004604827],"study_design_scores_gemma":[0.001898779,0.0009165208,0.9789835,0.0001338102,0.00007461682,0.00007845251,0.0001082988,0.0003340275,0.01666308,0.0003648287,0.0003618851,0.00008219726],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957656,0.0007433412,0.0001820641,0.002451509,0.0002541209,0.0003870153,0.000101438,0.0000137853,0.0001010814],"genre_scores_gemma":[0.9976469,0.0005709029,0.0006161408,0.0008567821,0.00007754441,0.00003460302,0.00003358865,0.00001869965,0.0001448193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3263324,"threshold_uncertainty_score":0.3799619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07053337819889587,"score_gpt":0.3905661236303832,"score_spread":0.3200327454314874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}