{"id":"W2081411799","doi":"10.1210/me.2008-0188","title":"Structure and Activity of the Human Growth Hormone Receptor (<i>hGHR</i>) Gene V2 Promoter","year":2008,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Montreal Children's Hospital","funders":"","keywords":"Biology; Alternative splicing; Gene; Promoter; Gene isoform; Growth hormone receptor; Housekeeping gene; Exon; Transcription (linguistics); 5' flanking region; Molecular biology; Genetics; Gene expression; Growth hormone; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003536056,0.0002535733,0.0004589779,0.0001217831,0.0001610047,0.000004852731,0.0001856043,0.0001734917,0.00003688129],"category_scores_gemma":[0.00008071413,0.0001803414,0.0001450835,0.000230439,0.0004814579,0.00006193096,0.0001964843,0.0004497385,0.000006198502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003608688,"about_ca_system_score_gemma":0.00006728971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009983212,"about_ca_topic_score_gemma":0.000002123481,"domain_scores_codex":[0.9985126,0.0001167905,0.0002799174,0.0003896214,0.000259824,0.0004411963],"domain_scores_gemma":[0.9990701,0.00001934579,0.000141927,0.0005241703,0.0001222923,0.0001221406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008312846,0.0001045778,0.03457007,0.00003650893,0.0001156806,0.000142649,0.0001767178,2.545291e-7,0.9631075,0.0005617421,0.0006689485,0.0004321779],"study_design_scores_gemma":[0.001224386,0.000389902,0.2742973,0.000008044531,0.00006925505,0.0007273046,0.000007540155,0.00000331679,0.722441,0.0001755459,0.0005292444,0.000127195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965473,0.000817561,0.0001168716,0.001192421,0.000128484,0.0004554162,0.00002442378,0.0000493649,0.0006682025],"genre_scores_gemma":[0.998521,0.0001925772,0.0004531399,0.0004979639,0.00006627923,0.0000134907,0.00001626261,0.00003749118,0.0002018205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2406666,"threshold_uncertainty_score":0.7354109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01301776939385488,"score_gpt":0.2330760995994196,"score_spread":0.2200583302055647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}