{"id":"W2081411799","doi":"10.1210/me.2008-0188","title":"Structure and Activity of the Human Growth Hormone Receptor (<i>hGHR</i>) Gene V2 Promoter","year":2008,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Montreal Children's Hospital","funders":"","keywords":"Biology; Alternative splicing; Gene; Promoter; Gene isoform; Growth hormone receptor; Housekeeping gene; Exon; Transcription (linguistics); 5' flanking region; Molecular biology; Genetics; Gene expression; Growth hormone; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001906606,0.0002910752,0.0001816869,0.0002739467,0.0001639528,0.0005958595,0.0002554941,0.0002135295,0.000737914],"category_scores_gemma":[0.0002655815,0.0002469909,0.0003771208,0.0001916313,0.0002831225,0.0001704219,0.0002151153,0.000378567,0.000494615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005748683,"about_ca_system_score_gemma":0.0005673919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002388504,"about_ca_topic_score_gemma":0.001700723,"domain_scores_codex":[0.999685,0.00003766722,0.00001983334,0.0001337366,0.0000667088,0.00005702745],"domain_scores_gemma":[0.9998379,0.00004337681,0.0000327341,0.00001719316,0.0000353549,0.0000334103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001545217,0.00002533418,0.0007920564,0.00003462666,0.000004745144,0.0000325355,0.00004456054,0.0001784565,0.9958352,0.0002831588,0.00004595427,0.002568746],"study_design_scores_gemma":[0.00003933913,0.0003205677,0.01612011,0.00003618527,0.00002727407,0.0003940524,0.00008430612,0.003092184,0.9730098,0.00024081,0.006616645,0.00001886272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9595584,0.003869464,0.02971259,0.0001631047,0.00005477658,0.000121933,0.001986169,0.0001771214,0.004356429],"genre_scores_gemma":[0.9643503,0.001464144,0.01921462,0.000120086,0.00003264491,0.0001157801,0.008508474,0.00009808761,0.006095828],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002388504,"threshold_uncertainty_score":0.004749179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01301776939385488,"score_gpt":0.2330760995994196,"score_spread":0.2200583302055647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}