{"id":"W2081413935","doi":"10.1016/j.ejcb.2005.11.004","title":"Oxidative stress is not required for the induction of apoptosis upon glutamine starvation of Sp2/0-Ag14 hybridoma cells","year":2006,"lang":"en","type":"article","venue":"European Journal of Cell Biology","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"Laurentian University","funders":"Natural Sciences and Engineering Research Council of Canada; Center for Undergraduate Research and Scholarship, Bowling Green State University","keywords":"Oxidative stress; Glutamine; Buthionine sulfoximine; Glutathione; Programmed cell death; Intracellular; Apoptosis; Viability assay; Cell biology; Reactive oxygen species; Cell culture; Biochemistry; Chemistry; Biology; Molecular biology; Enzyme; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006645657,0.000137678,0.0002327175,0.00006900939,0.00005068605,0.000007651555,0.0002710291,0.00007349128,0.00001504082],"category_scores_gemma":[0.00008007295,0.00009695125,0.0001644254,0.00009141424,0.000169038,0.000008673615,0.00005628311,0.0001066557,0.000001392144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001211711,"about_ca_system_score_gemma":0.00006706934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009653773,"about_ca_topic_score_gemma":0.000001007788,"domain_scores_codex":[0.9986418,0.0002703686,0.0006539261,0.0001735776,0.0001052332,0.0001550511],"domain_scores_gemma":[0.9981608,0.00007381465,0.001072379,0.0002111733,0.0004534661,0.0000283849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004007678,0.00006830853,0.0002285169,0.00006367857,0.00006299622,0.000001204186,0.00006653945,0.0002254174,0.9948427,0.00003129591,0.0007734759,0.003235093],"study_design_scores_gemma":[0.0009075237,0.001260159,0.0004081592,0.00002489475,0.00006855368,0.000009060727,0.0001467277,0.00003081491,0.9844113,0.00006589373,0.0125708,0.0000961409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802862,0.0007893543,0.0174916,0.0001301414,0.0003190564,0.00013126,0.00006987873,0.00000204775,0.0007804856],"genre_scores_gemma":[0.9968494,0.0005035928,0.001672236,0.00005201035,0.0005843208,0.000001534029,0.00006751047,0.00002116985,0.0002482476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0165632,"threshold_uncertainty_score":0.3953557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01274178173046559,"score_gpt":0.2307632411267606,"score_spread":0.218021459396295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}