{"id":"W2081436887","doi":"10.1136/bjo.87.5.635","title":"Predictive DNA testing in ophthalmology: View 2","year":2003,"lang":"en","type":"letter","venue":"British Journal of Ophthalmology","topic":"Ocular Oncology and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Hospital for Sick Children; University of Toronto; University Health Network","keywords":"Predictive testing; Genetic testing; Daughter; Genetics; Inheritance (genetic algorithm); Genetic counseling; Girl; Missense mutation; Test (biology); Medicine; Mutation; Gene; Biology; Evolutionary biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.000795186,0.0004550635,0.002017849,0.0005550195,0.00009479652,0.00002546859,0.0003254721,0.002214509,0.001196652],"category_scores_gemma":[0.001429652,0.0004950131,0.0004225065,0.0004270973,0.000375394,0.0001317095,0.00007541422,0.005073649,0.00005945473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004248662,"about_ca_system_score_gemma":0.0008710583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009146067,"about_ca_topic_score_gemma":8.35542e-7,"domain_scores_codex":[0.9959885,0.0009555144,0.001341949,0.000523952,0.0004135846,0.0007764239],"domain_scores_gemma":[0.9972762,0.0006306079,0.001083155,0.0003026139,0.0005347791,0.000172568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001531134,0.0004737742,0.07996564,0.0002118584,0.0006441528,0.8038227,0.00001975623,0.000003594018,0.00001486593,8.095241e-7,0.1131818,0.00150794],"study_design_scores_gemma":[0.003524603,0.003588598,0.08455955,0.001632324,0.0005726978,0.8830725,0.00002029114,0.00000261057,0.00002116622,0.0006715919,0.0220691,0.0002649796],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8489623,0.0236322,0.000009305237,0.07084808,0.003122804,0.001032706,0.00008552042,0.00002443784,0.05228265],"genre_scores_gemma":[0.7708279,0.0009274949,0.008018129,0.2008107,0.006910949,0.0001284703,0.0003930726,0.0004335225,0.01154977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1299626,"threshold_uncertainty_score":0.9997501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04274581530616713,"score_gpt":0.3145503665742971,"score_spread":0.27180455126813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}