{"id":"W2081505696","doi":"10.1186/1471-2121-11-56","title":"Hydrogen peroxide stimulates nuclear import of the POU homeodomain protein Oct-1 and its repressive effect on the expression of Cdx-2","year":2010,"lang":"en","type":"article","venue":"BMC Cell Biology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Canada Research Chairs; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Biology; PAX4; Homeobox; Protein kinase A; Molecular biology; Cell biology; Gene expression; Kinase; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000345204,0.0001127852,0.0002910953,0.00003629434,0.00005510696,0.000002073243,0.0001020765,0.0001453162,0.0002270725],"category_scores_gemma":[0.0007259541,0.00005066406,0.00008473565,0.00006418273,0.0001835734,0.0000120657,0.00008149632,0.0001836042,0.00001179702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005093436,"about_ca_system_score_gemma":0.00003159512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000162176,"about_ca_topic_score_gemma":0.000001149374,"domain_scores_codex":[0.9992179,0.00016671,0.0002035425,0.0001948368,0.00008298737,0.0001340057],"domain_scores_gemma":[0.9988148,0.0005339626,0.0001809593,0.000383191,0.00003819031,0.00004892091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003069358,0.00005489497,0.04244996,0.00008055449,0.00001368598,6.664649e-7,0.00007959842,0.000002060018,0.956589,0.0002290247,0.0001098199,0.00008372645],"study_design_scores_gemma":[0.0009842182,0.0007040106,0.01504085,0.00008520738,0.00004254509,0.000004808653,0.00005298601,0.0001439233,0.982178,0.0001251032,0.0005871506,0.00005117145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958448,0.000215103,7.747875e-7,0.0001447569,0.00007587062,0.0007151563,0.000008490547,0.00001514165,0.002979843],"genre_scores_gemma":[0.9993241,0.000006667232,0.00008192439,0.0001165906,0.00004384156,0.00002236265,0.000004524945,0.00001132482,0.0003886584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02740911,"threshold_uncertainty_score":0.2486284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009413034007934792,"score_gpt":0.2336496772433741,"score_spread":0.2242366432354393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}