{"id":"W2081527460","doi":"10.4161/cc.3.4.818","title":"Splitting the Apoptosome","year":2004,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Apoptosome; Biology; Caspase; Cell biology; Cytochrome c; Caspase-9; Mitochondrion; Context (archaeology); Intrinsic apoptosis; Apoptosis; Caspase 2; Biochemistry; Programmed cell death","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002040255,0.0004028724,0.0004280674,0.0004148322,0.0004663268,0.0007956484,0.0002801974,0.000609817,0.003591798],"category_scores_gemma":[0.0002058923,0.0001587821,0.0003562385,0.0002669468,0.0002880229,0.001014046,0.0007381043,0.001271669,0.003457052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003964552,"about_ca_system_score_gemma":0.00035122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001666005,"about_ca_topic_score_gemma":0.0002252058,"domain_scores_codex":[0.9997916,0.00001618323,0.00001467337,0.00004939932,0.00007525942,0.00005303248],"domain_scores_gemma":[0.9998332,0.00001577628,0.00002657863,0.00003062383,0.00005126536,0.0000425556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001302247,0.00003530157,0.000222586,0.0001944882,0.00001242781,0.0002158009,0.00007551492,0.00008204958,0.9687529,0.005565674,0.001298326,0.02341453],"study_design_scores_gemma":[0.00003173719,0.0002310528,0.00128581,0.00003069416,0.00001756044,0.001689799,0.0000845686,0.000481803,0.9138975,0.004238491,0.07799296,0.00001811189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7385083,0.03729981,0.1516202,0.003781674,0.002354381,0.0007327216,0.002934539,0.002022002,0.06074624],"genre_scores_gemma":[0.8874115,0.01547718,0.0345876,0.001573055,0.0002183137,0.0002223556,0.003375511,0.0002042817,0.05693014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003591798,"threshold_uncertainty_score":0.01201576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003901098952299771,"score_gpt":0.1997644160786432,"score_spread":0.1958633171263435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}