{"id":"W2081528639","doi":"10.1523/jneurosci.3828-08.2008","title":"Genetic Variants of Nogo-66 Receptor with Possible Association to Schizophrenia Block Myelin Inhibition of Axon Growth","year":2008,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Institutes of Health; Dr. Ralph and Marian Falk Medical Research Trust; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Yale University","keywords":"Schizophrenia (object-oriented programming); Endophenotype; Genetic association; Neuroscience; Biology; Myelin-associated glycoprotein; Haploinsufficiency; Myelin; Genetics; Gene; Single-nucleotide polymorphism; Psychology; Genotype; Central nervous system; Phenotype; Cognition; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003130629,0.0008190695,0.0003028957,0.0009157477,0.000319445,0.000198322,0.0002819274,0.0004318233,0.001854197],"category_scores_gemma":[0.0006133596,0.0002122194,0.000275518,0.0003935068,0.0003941217,0.0001017378,0.0002869572,0.0002734885,0.0002066649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002153351,"about_ca_system_score_gemma":0.0002036636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001818515,"about_ca_topic_score_gemma":0.003044817,"domain_scores_codex":[0.9997501,0.00005967656,0.00003962091,0.00006413934,0.0000561178,0.00003035093],"domain_scores_gemma":[0.9995877,0.0001079329,0.0001867595,0.00002829454,0.00002013322,0.00006925882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002332629,0.000199781,0.1014486,0.0001249076,0.0005613671,0.009820117,0.0003022052,0.0008800198,0.8736022,0.001051248,0.0002514258,0.009425388],"study_design_scores_gemma":[0.0002858341,0.001431597,0.8419882,0.00007828427,0.001028752,0.04162994,0.0003085409,0.004236957,0.1038709,0.001589317,0.003466632,0.00008499039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987589,0.0003353301,0.0004955092,0.00003674831,0.000007336299,0.000005759355,0.0001300068,0.00001430415,0.0002159983],"genre_scores_gemma":[0.9987065,0.0002364117,0.0006024595,0.00002506253,0.000007302201,0.000005472111,0.0001576419,0.00001225525,0.0002470968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001854197,"threshold_uncertainty_score":0.006202936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307046907139009,"score_gpt":0.2289103900468698,"score_spread":0.2158399209754797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}