{"id":"W2081529909","doi":"10.1016/s0168-3659(01)00537-5","title":"The effect of fatty acid substitution on the in vitro release of amphotericin B from micelles composed of poly(ethylene oxide)-block-poly(N-hexyl stearate-?-aspartamide)","year":2002,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":97,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Micelle; Chemistry; Stearic acid; Ethylene oxide; Lecithin; Drug carrier; Fatty acid; Amphiphile; Ethylene glycol; Stearate; Organic chemistry; Chromatography; Drug delivery; Aqueous solution; Copolymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004075383,0.0003726324,0.0002775325,0.0001446711,0.0001894976,0.0003362108,0.0002425846,0.0004638669,0.0009895081],"category_scores_gemma":[0.0007364317,0.0002864712,0.0002582835,0.0001833342,0.0003907735,0.0004727064,0.0001524465,0.0004775403,0.0003437128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002555348,"about_ca_system_score_gemma":0.0002970689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001075145,"about_ca_topic_score_gemma":0.0009331786,"domain_scores_codex":[0.9997457,0.00007919733,0.00004535108,0.00003591897,0.00004028173,0.00005357982],"domain_scores_gemma":[0.9993629,0.000324163,0.0001177254,0.00004718346,0.00007215652,0.00007591766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002277199,0.00006781272,0.0002385246,0.00006021015,0.00001560848,0.00008986673,0.00004465985,0.0001559716,0.9958012,0.00004832313,0.00002418611,0.001176548],"study_design_scores_gemma":[0.00005036864,0.0006254354,0.0009124785,0.000004982478,0.00002336779,0.00005935572,0.00001391099,0.0005479128,0.9974439,0.00001282823,0.0002979629,0.000007401215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997943,0.000938217,0.0003756993,0.00004077859,0.00003181123,0.00001140302,0.000101136,0.00001408778,0.0005439539],"genre_scores_gemma":[0.9981603,0.000458435,0.0005385486,0.00002517146,0.00001016719,0.000008987177,0.0001208596,0.00001040112,0.000667191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001075145,"threshold_uncertainty_score":0.003310204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03395830021321746,"score_gpt":0.3259200973693336,"score_spread":0.2919617971561162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}