{"id":"W2081573122","doi":"10.1038/sj.cgt.7700429","title":"Adenovirus-mediated CD40 ligand gene-engineered dendritic cells elicit enhanced CD8+ cytotoxic T-cell activation and antitumor immunity","year":2002,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University; University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"CD40; Cytotoxic T cell; CD80; CD86; Dendritic cell; Antigen-presenting cell; CD8; T cell; Immune system; Biology; Cancer research; Immunology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001918654,0.0004119939,0.0004828983,0.0002112193,0.0004029465,0.00004996624,0.0003296108,0.0003394096,0.001597231],"category_scores_gemma":[0.00002438759,0.0003871191,0.0001187751,0.0003189573,0.0002444746,0.0002180701,0.00004306585,0.0004461051,0.0003040085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001010707,"about_ca_system_score_gemma":0.00007793885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001414901,"about_ca_topic_score_gemma":0.000006609726,"domain_scores_codex":[0.9981701,0.0003103592,0.0004261012,0.0004276058,0.0000720859,0.0005937142],"domain_scores_gemma":[0.9989225,0.0002253225,0.0001856214,0.0005136957,0.0001091584,0.00004372574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008843969,0.0002225048,0.00005385952,0.00001976777,0.0002649442,0.000003259698,0.001374094,0.00002386462,0.9882506,0.000003590931,0.0006241789,0.008274909],"study_design_scores_gemma":[0.004609317,0.000408309,0.001811215,0.00004821263,0.00002570617,0.00002455894,0.000113389,0.00002099172,0.9801111,0.00001191958,0.01236363,0.0004517032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9013052,0.0966513,0.000344853,0.0001441149,0.0007049496,0.0005045453,0.00007505235,0.0001346796,0.0001353089],"genre_scores_gemma":[0.9257157,0.0697949,0.00005781672,0.0006858425,0.00008377269,0.0001282268,0.00007884886,0.00006729561,0.003387565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0268564,"threshold_uncertainty_score":0.9998581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01688747832361174,"score_gpt":0.2342646656273272,"score_spread":0.2173771873037154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}