{"id":"W2081573122","doi":"10.1038/sj.cgt.7700429","title":"Adenovirus-mediated CD40 ligand gene-engineered dendritic cells elicit enhanced CD8+ cytotoxic T-cell activation and antitumor immunity","year":2002,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University; University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"CD40; Cytotoxic T cell; CD80; CD86; Dendritic cell; Antigen-presenting cell; CD8; T cell; Immune system; Biology; Cancer research; Immunology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003248026,0.0006336361,0.0004355562,0.0003914084,0.0001777148,0.000645733,0.0001651643,0.0005323802,0.001705682],"category_scores_gemma":[0.0002021907,0.0002451155,0.0002845649,0.0002129586,0.0003023305,0.0003673881,0.0002820628,0.001311231,0.0007398599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004705794,"about_ca_system_score_gemma":0.0002701096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000219966,"about_ca_topic_score_gemma":0.0003117322,"domain_scores_codex":[0.9996618,0.00006233426,0.00003253157,0.00004715101,0.00007147039,0.0001246717],"domain_scores_gemma":[0.9998165,0.00006720903,0.00002379342,0.00003374041,0.00002211071,0.00003657369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002670808,0.0001037979,0.00009707134,0.00003501417,0.000005038539,0.00003366634,0.00001920489,0.0001041171,0.997503,0.0002263598,0.0000657975,0.001539963],"study_design_scores_gemma":[0.00009867837,0.0003134524,0.0009252474,0.000004437662,0.00002034782,0.000169351,0.00002272895,0.001064924,0.9956375,0.000113024,0.001626362,0.000004065488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926508,0.001073725,0.003345685,0.0001364317,0.00009251144,0.0000650882,0.0002645569,0.0001352868,0.002235855],"genre_scores_gemma":[0.9947187,0.0004188049,0.001721506,0.00006400899,0.00002841576,0.00003565128,0.0002824362,0.00002940909,0.002700965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001705682,"threshold_uncertainty_score":0.005706072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01688747832361174,"score_gpt":0.2342646656273272,"score_spread":0.2173771873037154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}