{"id":"W2081592335","doi":"10.1038/nature07929","title":"Gene regulatory logic of dopamine neuron differentiation","year":2009,"lang":"en","type":"article","venue":"Nature","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":260,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institutes of Health; University of British Columbia; National Institute of Neurological Disorders and Stroke; Howard Hughes Medical Institute","keywords":"Dopamine; Dopaminergic; Neuroscience; Biology; Dopaminergic pathways","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002574567,0.0001559145,0.0002281057,0.0003810597,0.000290975,0.0007908322,0.0004645623,0.0003434458,0.00122708],"category_scores_gemma":[0.0003732464,0.0001665436,0.0002104514,0.0001649114,0.0007654659,0.0004846876,0.0002538452,0.0005892933,0.0002806387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000871281,"about_ca_system_score_gemma":0.0005476486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005722623,"about_ca_topic_score_gemma":0.001088376,"domain_scores_codex":[0.999826,0.00002544189,0.000008842228,0.00006045627,0.00004491302,0.00003439364],"domain_scores_gemma":[0.9998171,0.00005748917,0.00002220082,0.00002255256,0.00004314643,0.00003755992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002955717,0.00004944692,0.002182538,0.000061907,0.00001483463,0.0004605612,0.0001638506,0.002579395,0.7258177,0.2455697,0.001078303,0.02172619],"study_design_scores_gemma":[0.0001494082,0.0003982094,0.0148921,0.00006216901,0.00006686039,0.0009978862,0.000340609,0.02494039,0.7023153,0.2253931,0.03035783,0.00008617033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8391384,0.003893189,0.1098451,0.003921457,0.000563468,0.00006319076,0.000720788,0.0004883274,0.04136602],"genre_scores_gemma":[0.9838098,0.0008971394,0.009529556,0.0002855927,0.00005367542,0.0000407804,0.0001464807,0.00003946124,0.005197434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00122708,"threshold_uncertainty_score":0.006321669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005506901857754563,"score_gpt":0.2237044636101163,"score_spread":0.2181975617523617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}