{"id":"W2081655256","doi":"10.1016/j.mod.2003.09.001","title":"Differential activities of Sonic hedgehog mediated by Gli transcription factors define distinct neuronal subtypes in the dorsal thalamus","year":2003,"lang":"en","type":"article","venue":"Mechanisms of Development","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Sonic hedgehog; Biology; Thalamus; Neuroscience; Transcription factor; Morphogen; Hedgehog; Hedgehog signaling pathway; Sensory system; Dorsum; Cell biology; Signal transduction; Anatomy; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001604676,0.0002466332,0.000395307,0.0007106294,0.0002139538,0.0009683182,0.0004028777,0.0002167231,0.0005476612],"category_scores_gemma":[0.0002849338,0.0003359371,0.0003257009,0.0003146806,0.0006485401,0.0005928599,0.0005140053,0.0006001361,0.000288288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007603756,"about_ca_system_score_gemma":0.0003728816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003321007,"about_ca_topic_score_gemma":0.006154129,"domain_scores_codex":[0.9997935,0.00002032261,0.000015306,0.0000327845,0.00006645574,0.00007168098],"domain_scores_gemma":[0.9998234,0.0000360004,0.00003598052,0.00001540535,0.00003671618,0.00005248923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001800181,0.00000512569,0.001589354,0.00004064099,0.000008467211,0.00008588562,0.0001447442,0.00003556723,0.9936644,0.001126444,0.00002311245,0.003096275],"study_design_scores_gemma":[0.00006300322,0.0002931432,0.1273952,0.000053077,0.00007987142,0.001266457,0.001028505,0.001127111,0.864897,0.001115226,0.0026507,0.00003071873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874567,0.002826778,0.005649475,0.00007149862,0.00001604934,0.00002135412,0.0002450618,0.00003577695,0.003677267],"genre_scores_gemma":[0.9911335,0.001674508,0.00314075,0.00007770611,0.00001327665,0.00003724897,0.0004660562,0.00003698646,0.003420043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003321007,"threshold_uncertainty_score":0.00660336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01420973938378878,"score_gpt":0.2143038734134776,"score_spread":0.2000941340296889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}