{"id":"W2081758137","doi":"10.1016/j.stem.2009.03.014","title":"Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens","year":2009,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":1054,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University; Toronto Western Hospital; University of Toronto; University Health Network; SickKids Foundation; Hospital for Sick Children; Ontario Institute for Cancer Research","funders":"Biotechnology and Biological Sciences Research Council; Hospital for Sick Children; Christ's College, University of Cambridge; National Cancer Institute; University of Toronto; Cancer Research UK; Medical Research Council; Ontario Genomics; Directorate for Biological Sciences; Ontario Genomics Institute; Stem Cell Network; Genome Canada","keywords":"Biology; Phenotype; Glioma; Stem cell; Cell culture; Cancer research; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002481813,0.0005278816,0.0005698297,0.0007739972,0.0003611284,0.0005192949,0.0004136381,0.0004150051,0.002729806],"category_scores_gemma":[0.0002334045,0.0002079727,0.000426112,0.0005851834,0.0003000391,0.0002283237,0.0002834709,0.0008108021,0.002171288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002893437,"about_ca_system_score_gemma":0.0003364242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00202796,"about_ca_topic_score_gemma":0.005513187,"domain_scores_codex":[0.9996496,0.00004282378,0.0000378115,0.00003159631,0.0001962967,0.00004194263],"domain_scores_gemma":[0.9996682,0.00008205068,0.00006145036,0.00006455647,0.00007975096,0.00004394517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000480872,0.00003694654,0.0002606121,0.00003424575,0.000008543623,0.000131925,0.00004789219,0.00005260229,0.995243,0.0003603701,0.0003253047,0.003450539],"study_design_scores_gemma":[0.000008420501,0.00008210334,0.001374005,0.000003252302,0.00002755365,0.0002210923,0.00003312018,0.000249941,0.9909848,0.0000845609,0.006925941,0.000005236632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8313336,0.002909285,0.1187622,0.0005870411,0.0002375516,0.001147084,0.01397849,0.002223793,0.02882086],"genre_scores_gemma":[0.8702069,0.003553936,0.06655458,0.0002338671,0.00004865313,0.0007367933,0.02346517,0.0008556176,0.03434451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002729806,"threshold_uncertainty_score":0.009132087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02227744772172283,"score_gpt":0.2445286797848953,"score_spread":0.2222512320631725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}