{"id":"W2081781900","doi":"10.1158/0008-5472.sabcs10-p6-09-09","title":"Abstract P6-09-09: Dual Estrogen Effects on Breast Cancer: Endogenous Estrogen Stimulates, Exogenous Estrogen Protects. Further Investigation of Estrogen Chemoprevention Is Warranted","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Estrogen; Medicine; Breast cancer; Tamoxifen; Internal medicine; Oophorectomy; Raloxifene; Selective estrogen receptor modulator; Progestin; Estrogen receptor; Endocrinology; Hormone replacement therapy (female-to-male); Cancer; Oncology; Hysterectomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001809254,0.0004887084,0.0009568849,0.000404446,0.000189631,0.001233997,0.0007723233,0.002125645,0.06122592],"category_scores_gemma":[0.001615381,0.00015917,0.0006634687,0.0005137591,0.000485535,0.000664968,0.0004238746,0.001856782,0.01147431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003457176,"about_ca_system_score_gemma":0.0008217307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004983891,"about_ca_topic_score_gemma":0.0008507257,"domain_scores_codex":[0.9995733,0.0001796238,0.00004105527,0.00005346708,0.0001189892,0.00003349673],"domain_scores_gemma":[0.9983974,0.0007213973,0.0003267998,0.00009188215,0.0002532466,0.0002091845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.09291883,0.001902365,0.002598879,0.02392426,0.0009236805,0.0004305999,0.00005808156,0.000303919,0.01775239,0.007326826,0.1882637,0.6635965],"study_design_scores_gemma":[0.05863427,0.05995866,0.04066256,0.01171843,0.003954672,0.001845081,0.0002110096,0.0008467381,0.02106467,0.01649052,0.7845258,0.00008760458],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.1045288,0.6020373,0.003712995,0.1092274,0.01933484,0.003242685,0.03079724,0.0007464188,0.1263724],"genre_scores_gemma":[0.4006118,0.3539096,0.006441116,0.05137863,0.0259314,0.001464727,0.01478831,0.0002795746,0.1451949],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.06122592,"threshold_uncertainty_score":0.2048211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02609368263559171,"score_gpt":0.3189357191758311,"score_spread":0.2928420365402394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}