{"id":"W2081837231","doi":"10.1139/y06-002","title":"G-protein-coupled receptors, channels, and Na+–H+exchanger in nuclear membranes of heart, hepatic, vascular endothelial, and smooth muscle cellsThis paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell.","year":2006,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Receptor; Transcellular; Cell biology; Angiotensin II; Ion channel; Endothelin receptor; Biophysics; Biology; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006152795,0.0003107692,0.001130892,0.0004617336,0.00008730594,0.00001402199,0.0001746231,0.0005708215,0.009498523],"category_scores_gemma":[0.00005498412,0.0002556402,0.0002220858,0.0002755045,0.0004035539,0.0000272793,0.00004494127,0.0004427798,0.000001272017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004704586,"about_ca_system_score_gemma":0.0004498354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002158183,"about_ca_topic_score_gemma":0.0005683996,"domain_scores_codex":[0.9977294,0.0006145861,0.0008657271,0.0003634633,0.0001208822,0.000305891],"domain_scores_gemma":[0.9987152,0.00009100613,0.000706688,0.0001451742,0.0001759937,0.0001659105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008741217,0.0004926769,0.0001704373,0.01226113,0.0007135265,0.00001752478,0.005812992,0.001456031,0.9458501,0.00002185002,0.02164787,0.01068174],"study_design_scores_gemma":[0.002819395,0.0009526338,0.00007674727,0.000541846,0.0004738058,0.00003057818,0.0003731181,0.001308798,0.04697098,0.00005726137,0.9460155,0.0003793601],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6911141,0.3061171,0.000002037215,0.0003220711,0.0008485502,0.001131425,0.0001566516,0.000003463341,0.0003046741],"genre_scores_gemma":[0.3963161,0.5999688,0.0001113141,0.0005138262,0.002317518,0.00003840819,0.0001130214,0.00008059273,0.0005403971],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9243676,"threshold_uncertainty_score":0.9999896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01020690474283772,"score_gpt":0.2269395859563836,"score_spread":0.2167326812135458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}