{"id":"W2081868893","doi":"10.1002/jor.20658","title":"Effect of cell‐based VEGF gene therapy on healing of a segmental bone defect","year":2008,"lang":"en","type":"article","venue":"Journal of Orthopaedic Research®","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"University of Toronto; Physicians' Services Incorporated Foundation","keywords":"Angiogenesis; Bone healing; Vascular endothelial growth factor; CD31; Medicine; Genetic enhancement; Ossification; Wound healing; Pathology; VEGF receptors; Surgery; Internal medicine; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002183303,0.0004132164,0.0004294563,0.0002623879,0.0001256385,0.0002580854,0.0002431962,0.0004230223,0.0008265494],"category_scores_gemma":[0.0001811811,0.0001294686,0.0002598525,0.0001187787,0.000422584,0.0001753385,0.0001464753,0.0004135496,0.0001914507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001638511,"about_ca_system_score_gemma":0.0002651956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008218893,"about_ca_topic_score_gemma":0.000959719,"domain_scores_codex":[0.9998099,0.0000397671,0.00001310375,0.00002993511,0.00005852961,0.00004875705],"domain_scores_gemma":[0.9998902,0.00003513822,0.00002487283,0.000009405758,0.000009242388,0.00003097308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006557015,0.0003881141,0.0001303964,0.0001036999,0.00001510519,0.00007343238,0.00003176602,0.0003262505,0.9924078,0.0001229754,0.00005077247,0.005693808],"study_design_scores_gemma":[0.0002089608,0.01035926,0.001408344,0.00001835214,0.00006146607,0.0002707113,0.00003477785,0.001789464,0.984506,0.00004297936,0.001291365,0.000008300381],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969914,0.001141196,0.001154536,0.00004395495,0.00004437043,0.00004197764,0.00003179906,0.00003375733,0.0005170392],"genre_scores_gemma":[0.9956987,0.00108791,0.002063161,0.00003131031,0.00001704658,0.00004252014,0.00007549756,0.000008369941,0.0009754017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008265494,"threshold_uncertainty_score":0.002765059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.041385659962858,"score_gpt":0.361895480294467,"score_spread":0.320509820331609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}