{"id":"W2081949544","doi":"10.1002/pros.10353","title":"Inhibition of cell signaling by the combi‐nitrosourea FD137 in the androgen independent DU145 prostate cancer cell line","year":2003,"lang":"en","type":"article","venue":"The Prostate","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Health Canada; Royal Victoria Hospital; Royal Victoria Regional Health Centre","funders":"","keywords":"DU145; Cancer research; DNA damage; Epidermal growth factor receptor; Comet assay; Androgen receptor; Biology; Prostate; Signal transduction; Lomustine; Nitrosourea; Cell culture; Prostate cancer; Molecular biology; Chemistry; Cancer; Cell biology; Internal medicine; DNA; Medicine; Receptor; Biochemistry; LNCaP","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009571108,0.0002627797,0.0001895659,0.0001415487,0.00008821438,0.000147339,0.0001555197,0.0001474464,0.0006919509],"category_scores_gemma":[0.00006549174,0.00006982121,0.00014024,0.0001184568,0.0001104673,0.00009131192,0.00007039234,0.000255603,0.0001359987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002812234,"about_ca_system_score_gemma":0.0002535791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001816156,"about_ca_topic_score_gemma":0.0026891,"domain_scores_codex":[0.9999163,0.00001308558,0.000007481784,0.0000132532,0.00003195674,0.00001791404],"domain_scores_gemma":[0.9999593,0.00001170173,0.000009318328,0.000005429567,0.000006170268,0.000007972548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005589709,0.00003808725,0.0001560318,0.00003139522,0.000003809628,0.00001958721,0.000008874646,0.00007172279,0.9983875,0.00005477633,0.00002141838,0.001150894],"study_design_scores_gemma":[0.00001516132,0.000531596,0.001611788,0.000001840779,0.00001172174,0.0001073634,0.000006814708,0.0005142535,0.9962998,0.000008704955,0.0008896599,0.000001282598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995972,0.001179629,0.001656107,0.00002974252,0.000008398172,0.00003100532,0.0002444558,0.00003921454,0.0008394581],"genre_scores_gemma":[0.9954743,0.0007554762,0.001837158,0.00001469453,0.000003550134,0.0000285207,0.0004373089,0.000005936494,0.001443192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001816156,"threshold_uncertainty_score":0.003611147,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02108184091933984,"score_gpt":0.2868484938339413,"score_spread":0.2657666529146015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}