{"id":"W2081984294","doi":"10.1006/viro.2000.0328","title":"Identification of Domains of the HPV11 E1 Protein Required for DNA Replication in Vitro","year":2000,"lang":"en","type":"article","venue":"Virology","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"Memorial Sloan-Kettering Cancer Center","keywords":"Biology; Primase; DNA replication; DNA polymerase; Pre-replication complex; Molecular biology; Control of chromosome duplication; DNA; Cell biology; Genetics; Gene; RNA; Reverse transcriptase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002480182,0.00006430392,0.0001120366,0.0000276329,0.00003024739,0.000001343039,0.0002267008,0.0001736206,0.00001097728],"category_scores_gemma":[0.00005956824,0.00005339029,0.00007355329,0.00009692569,0.000151284,0.000001441382,0.00003289144,0.00003783696,0.000001364373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006009184,"about_ca_system_score_gemma":0.00002549488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001115338,"about_ca_topic_score_gemma":0.00001253327,"domain_scores_codex":[0.9992192,0.00006897382,0.0003116667,0.0002586686,0.00003587056,0.000105615],"domain_scores_gemma":[0.9990655,0.0000078,0.0001675995,0.000704013,0.00004312769,0.00001197318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000136781,0.00006283943,0.00009501049,0.00000970906,0.000008366408,4.284534e-8,0.00001049641,0.000008059489,0.9941421,0.001369586,0.00009220792,0.004064807],"study_design_scores_gemma":[0.00025654,0.0001065847,0.005568403,0.000002898065,0.000007891848,0.000003153347,0.000003377553,0.00007862017,0.9837868,0.001939556,0.008198434,0.00004777728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921138,0.00007023577,0.006105647,0.0006135375,0.00001155431,0.0007811697,0.0000460291,0.000005024207,0.0002529838],"genre_scores_gemma":[0.997761,0.00002770027,0.001078973,0.0001172966,0.00002098188,0.0004818458,0.000091192,0.00000867935,0.0004123154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01035533,"threshold_uncertainty_score":0.2177193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00729082536392152,"score_gpt":0.2631991221092813,"score_spread":0.2559082967453598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}