{"id":"W2081984294","doi":"10.1006/viro.2000.0328","title":"Identification of Domains of the HPV11 E1 Protein Required for DNA Replication in Vitro","year":2000,"lang":"en","type":"article","venue":"Virology","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"Memorial Sloan-Kettering Cancer Center","keywords":"Biology; Primase; DNA replication; DNA polymerase; Pre-replication complex; Molecular biology; Control of chromosome duplication; DNA; Cell biology; Genetics; Gene; RNA; Reverse transcriptase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000320388,0.0003808177,0.0004479343,0.0004273553,0.0003398348,0.0006407425,0.0003627217,0.0004004362,0.001351156],"category_scores_gemma":[0.0007317035,0.000410273,0.0004434281,0.0003577131,0.0003353153,0.0004887016,0.0003441327,0.0007907294,0.00109662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006327668,"about_ca_system_score_gemma":0.000386596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001454088,"about_ca_topic_score_gemma":0.001674198,"domain_scores_codex":[0.9997995,0.00005021567,0.00002248797,0.0000353556,0.000043666,0.00004872791],"domain_scores_gemma":[0.9992983,0.0003525613,0.00008294466,0.0001105386,0.00007182144,0.00008380544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001401532,0.00002633727,0.0003396757,0.00003743049,0.000002964529,0.00003992412,0.00002856998,0.0001183178,0.9983665,0.0001445449,0.00003994808,0.0007155376],"study_design_scores_gemma":[0.000007989653,0.00005017201,0.00413036,0.000007169888,0.0000109335,0.0002835625,0.00004702776,0.0006216728,0.992654,0.00007389323,0.002107773,0.000005426338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900653,0.001395221,0.005906973,0.0001465879,0.00002211423,0.0000380013,0.001026633,0.00006383215,0.001335285],"genre_scores_gemma":[0.981418,0.00079596,0.008613504,0.00008860132,0.0000150208,0.00005223586,0.006341494,0.00009532623,0.002579924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001454088,"threshold_uncertainty_score":0.004591048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00729082536392152,"score_gpt":0.2631991221092813,"score_spread":0.2559082967453598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}