{"id":"W2081993609","doi":"10.1074/jbc.m111.218719","title":"Adrenergic Regulation of AMP-activated Protein Kinase in Brown Adipose Tissue in Vivo","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"AMPK; Protein kinase A; Phosphorylation; AMP-activated protein kinase; Internal medicine; Endocrinology; Adipose tissue; Chemistry; Biology; Cell biology; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002772093,0.000117523,0.0004494478,0.00007516444,0.000007927492,0.000001978867,0.00009965349,0.0002468526,0.001191468],"category_scores_gemma":[0.000296666,0.00008066161,0.00007587802,0.0002264606,0.00007095183,0.00005751566,0.00002460072,0.000315507,0.00000242389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004480322,"about_ca_system_score_gemma":0.00006627657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000040181,"about_ca_topic_score_gemma":0.000003007663,"domain_scores_codex":[0.9989219,0.00004286202,0.0006015683,0.0001259038,0.0001436228,0.0001641465],"domain_scores_gemma":[0.9992564,0.00002299567,0.0003601377,0.0001358089,0.000106655,0.0001179488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008056476,0.0003838382,0.006341897,0.00006048355,0.00001952579,0.0001618557,0.0001417037,0.000002456351,0.9901528,0.00002016825,0.00003618547,0.001873446],"study_design_scores_gemma":[0.001317296,0.0002337773,0.08057144,0.0002658828,0.00002204844,0.0001435614,0.00003426556,0.00000223818,0.9150404,0.00032375,0.001968071,0.0000773151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964283,0.001110282,0.00001636303,0.0000592336,0.00002807999,0.000125496,0.000002542943,0.000006379749,0.002223317],"genre_scores_gemma":[0.9976906,0.00007054614,0.00142668,0.00002603648,0.000129537,0.000003733319,0.000004890541,0.000007061541,0.0006409184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07511243,"threshold_uncertainty_score":0.9997216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04372693473147696,"score_gpt":0.2770037300573318,"score_spread":0.2332767953258549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}