{"id":"W2082002716","doi":"10.3109/07435800009048592","title":"Molecular Modeling of the Hamster Adrenala P450C17","year":2000,"lang":"en","type":"article","venue":"Endocrine Research","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"U.S. Public Health Service","keywords":"Hamster; Pregnenolone; CYP17A1; Active site; Lyase; Enzyme; Dehydroepiandrosterone; Mutant; Biology; Biochemistry; Chemistry; Molecular biology; Steroid; Hormone; Gene; Androgen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002053201,0.0007113344,0.0007122997,0.0003256115,0.0006392752,0.00100588,0.001089919,0.001069377,0.008516798],"category_scores_gemma":[0.0003598692,0.0003896366,0.0007849969,0.000499466,0.000335723,0.0003639001,0.0004761817,0.0006487955,0.001061884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001097318,"about_ca_system_score_gemma":0.001338001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0140124,"about_ca_topic_score_gemma":0.006376957,"domain_scores_codex":[0.9998468,0.00002893512,0.000006496339,0.00002808447,0.00004955399,0.00004000968],"domain_scores_gemma":[0.9998661,0.00004373801,0.00002106957,0.000009547027,0.00003193314,0.00002747773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0004193571,0.0002273391,0.002970176,0.0004229385,0.0001633998,0.001157944,0.0002228228,0.9333621,0.03639578,0.01510105,0.002452004,0.00710508],"study_design_scores_gemma":[0.0002059818,0.0002331995,0.00134547,0.00003869504,0.0000565733,0.0001420264,0.0001529012,0.9808497,0.004898153,0.002802118,0.009242427,0.00003272279],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9187244,0.002443901,0.03956368,0.001066383,0.0001886994,0.0001554455,0.004132837,0.0009151421,0.03280953],"genre_scores_gemma":[0.9559693,0.002272454,0.02971965,0.0001704887,0.00003947873,0.0002615266,0.004657743,0.0002731871,0.006636092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0140124,"threshold_uncertainty_score":0.0284915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08020789204166674,"score_gpt":0.3972248518656433,"score_spread":0.3170169598239766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}