{"id":"W2082005805","doi":"10.1002/smll.201090092","title":"Nanopore Biosensors: Monitoring of an ATP‐Binding Aptamer and its Conformational Changes Using an α‐Hemolysin Nanopore (Small 1/2011)","year":2010,"lang":"en","type":"article","venue":"Small","topic":"Nanopore and Nanochannel Transport Studies","field":"Engineering","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Nanopore; Aptamer; Chemistry; Biophysics; Conformational change; DNA; Molecular beacon; Oligonucleotide; Biochemistry; Nanotechnology; Biology; Materials science; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002761724,0.0002910547,0.0002961315,0.0002183137,0.0001436514,0.0002336336,0.0004207066,0.000616767,0.0005837818],"category_scores_gemma":[0.0002409131,0.0001938075,0.0001891937,0.000115485,0.0001980293,0.0004986592,0.0002662714,0.0004133244,0.0002798196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003766806,"about_ca_system_score_gemma":0.0001486243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003836685,"about_ca_topic_score_gemma":0.0005962191,"domain_scores_codex":[0.9997267,0.00003389307,0.00001686958,0.00009287406,0.00009856465,0.00003097386],"domain_scores_gemma":[0.9998228,0.00005312439,0.00004584074,0.00001337235,0.00003927965,0.00002555444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001748085,0.00001373187,0.00006942121,0.00001772661,0.000002485692,0.0000170027,0.000006250102,0.00006095397,0.9983071,0.0000478393,0.00003992072,0.00140006],"study_design_scores_gemma":[0.000003643603,0.00007645241,0.0008438886,0.00000207592,0.000004334869,0.0001154175,0.000007829084,0.003883924,0.9943007,0.00004154204,0.0007127378,0.000007267409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8247177,0.0028918,0.1675042,0.0002369947,0.0002014356,0.0001220524,0.0006312465,0.001588155,0.002106339],"genre_scores_gemma":[0.8976347,0.0009962356,0.09684606,0.0002185888,0.00003089853,0.0001680019,0.0004251601,0.00004128234,0.003639022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000616767,"threshold_uncertainty_score":0.002733052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03802990484823861,"score_gpt":0.2396378743917724,"score_spread":0.2016079695435338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}