{"id":"W2082226143","doi":"10.1523/jneurosci.2925-11.2011","title":"Dual Regulation of Anterograde and Retrograde Transmission by Endocannabinoids","year":2011,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Heart and Stroke Foundation of Canada","keywords":"Postsynaptic potential; Dynorphin; Metabotropic glutamate receptor; Neuroscience; Excitatory postsynaptic potential; Neurotransmission; Retrograde signaling; Glutamate receptor; Postsynaptic Current; Chemistry; Inhibitory postsynaptic potential; Synaptic plasticity; Active zone; Biology; Synaptic vesicle; Receptor; Opioid peptide; Opioid; Biochemistry; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001346142,0.0003686357,0.0003918862,0.0003052133,0.0002219188,0.0004706108,0.0002625088,0.0002575291,0.0006197991],"category_scores_gemma":[0.0001658029,0.0001773191,0.0003172047,0.0001344149,0.0003965769,0.0004440012,0.0003934565,0.0006189758,0.0001633457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005802205,"about_ca_system_score_gemma":0.000293719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001298303,"about_ca_topic_score_gemma":0.002727639,"domain_scores_codex":[0.9998048,0.00002213454,0.000019589,0.00003427055,0.00006198244,0.0000573532],"domain_scores_gemma":[0.9998761,0.00001629037,0.00003258112,0.00002038167,0.00002805766,0.000026607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002038566,0.000009680566,0.0002625308,0.00005571679,0.000009963022,0.0001260154,0.00002439552,0.00006035203,0.9937303,0.0007171392,0.00002187213,0.004778211],"study_design_scores_gemma":[0.00004630969,0.0002487696,0.01295361,0.00002548628,0.00006455716,0.0005338067,0.00008266363,0.0009199541,0.9812003,0.000657354,0.003245889,0.00002129444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818867,0.007599613,0.00639576,0.0001921839,0.00006706071,0.00002685296,0.0001335751,0.00008135143,0.003616875],"genre_scores_gemma":[0.9907608,0.003509135,0.003676844,0.00005677139,0.00002145396,0.00002450944,0.00007109905,0.0000139853,0.001865357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001298303,"threshold_uncertainty_score":0.004209816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03179244398670989,"score_gpt":0.2910252249967393,"score_spread":0.2592327810100294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}