{"id":"W2082238995","doi":"10.1038/labinvest.2008.109","title":"Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats","year":2008,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":223,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lakehead University; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Internal medicine; Endocrinology; Insulin; Diabetes mellitus; Pancreatic islets; Insulin resistance; Pancreas; Medicine; Endogeny; Islet; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003870136,0.001359652,0.0007165557,0.002289834,0.0005812839,0.0005858428,0.000492154,0.0006561211,0.002407417],"category_scores_gemma":[0.0003432321,0.0008496119,0.0004868818,0.0008080081,0.001097892,0.0007981152,0.00039038,0.0015375,0.0003110574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006587464,"about_ca_system_score_gemma":0.0006130636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002588799,"about_ca_topic_score_gemma":0.002364176,"domain_scores_codex":[0.9997031,0.00003603807,0.00003818847,0.00007955784,0.00006263873,0.00008049748],"domain_scores_gemma":[0.9991943,0.00008366552,0.0002068537,0.0001077557,0.00005395371,0.0003533449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007121437,0.00031263,0.000976496,0.0000431235,0.00003018074,0.0001864973,0.00005703349,0.00009717614,0.989417,0.0001875868,0.00006326074,0.001507476],"study_design_scores_gemma":[0.000378298,0.001590205,0.009848365,0.00001094361,0.0001208614,0.0002829066,0.0001588952,0.0008312704,0.9856851,0.0002051963,0.0008580501,0.00002994429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998311,0.0003138397,0.0005315443,0.0001043437,0.00004193467,0.00001084927,0.000248307,0.00007180073,0.0003663665],"genre_scores_gemma":[0.9940931,0.0006026719,0.001633151,0.0001145768,0.0000437563,0.00004615944,0.0005433643,0.00006671625,0.002856527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002588799,"threshold_uncertainty_score":0.008053541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01064602593149118,"score_gpt":0.2155550004460293,"score_spread":0.2049089745145381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}