{"id":"W2082244680","doi":"10.1021/tx700422h","title":"Synthesis and Characterization of DNA Containing an<i>N</i><sup>1</sup>-2′-Deoxyinosine-ethyl-<i>N</i><sup>3</sup>-thymidine Interstrand Cross-Link: A Structural Mimic of the Cross-Link Formed by 1,3-Bis-(2-chloroethyl)-1-nitrosourea","year":2008,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"DNA; Thymidine; Chemistry; Characterization (materials science); Stereochemistry; Nanotechnology; Biochemistry; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0008619682,0.0003970117,0.000670041,0.0001246669,0.0002274619,0.00005057953,0.0009233716,0.000924044,0.00007967783],"category_scores_gemma":[0.001845356,0.0003355518,0.0001912664,0.0003702706,0.003094139,0.00004867189,0.0006350348,0.0008616858,0.000001557816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001106379,"about_ca_system_score_gemma":0.0003462839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004136324,"about_ca_topic_score_gemma":0.000005065451,"domain_scores_codex":[0.9964013,0.000293017,0.0009187153,0.0008502146,0.0005302675,0.00100649],"domain_scores_gemma":[0.997777,0.0004477788,0.0002800523,0.0007508303,0.0004262708,0.0003180388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001672459,0.000140456,0.02747946,0.0002093119,0.00007617171,0.00001236909,0.0004719879,0.00003837027,0.9685574,0.00001990588,0.0001102107,0.001211892],"study_design_scores_gemma":[0.001991272,0.000467809,0.006597612,0.00009510241,0.00001935999,0.0001113794,0.0001774882,0.001087594,0.9884778,0.0001518435,0.0005168798,0.0003058058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979947,0.00032077,0.00002822655,0.0006419713,0.00005157487,0.0004532831,0.0002721628,0.00001700224,0.0002202745],"genre_scores_gemma":[0.9984191,0.0003672076,0.0001423086,0.0001533448,0.0003238987,0.00008468005,0.0003270888,0.0000603798,0.0001219824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02088185,"threshold_uncertainty_score":0.9999096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02981085611734128,"score_gpt":0.3242527494744014,"score_spread":0.2944418933570601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}