{"id":"W2082244680","doi":"10.1021/tx700422h","title":"Synthesis and Characterization of DNA Containing an<i>N</i><sup>1</sup>-2′-Deoxyinosine-ethyl-<i>N</i><sup>3</sup>-thymidine Interstrand Cross-Link: A Structural Mimic of the Cross-Link Formed by 1,3-Bis-(2-chloroethyl)-1-nitrosourea","year":2008,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"DNA; Thymidine; Chemistry; Characterization (materials science); Stereochemistry; Nanotechnology; Biochemistry; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001218515,0.0002012001,0.0001208404,0.0001483925,0.00009948809,0.0001340771,0.0001419627,0.0002705462,0.0005875595],"category_scores_gemma":[0.0003142602,0.0001021472,0.0001097205,0.0001584063,0.0001526379,0.0001515733,0.00007433162,0.0002068703,0.0002667756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001121069,"about_ca_system_score_gemma":0.0001599975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00024594,"about_ca_topic_score_gemma":0.0003382982,"domain_scores_codex":[0.9999062,0.00001512506,0.000007808272,0.00003051473,0.00003127935,0.000009101187],"domain_scores_gemma":[0.999713,0.00006985433,0.00009277841,0.00002708501,0.000065238,0.00003200471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008759366,0.000005372642,0.0000400129,0.00001464641,8.426899e-7,0.00001231056,0.000009394634,0.0000433612,0.9993278,0.00002354008,0.00000318911,0.000510735],"study_design_scores_gemma":[0.00000190536,0.0001153552,0.0006265042,0.000001691364,0.000004220523,0.00006805696,0.000007939621,0.0001828356,0.9980885,0.00001093128,0.0008903451,0.000001725972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9734159,0.0006611157,0.02356419,0.00004108315,0.00001633587,0.00008562653,0.0005493789,0.00008240766,0.001583937],"genre_scores_gemma":[0.9683394,0.000642886,0.02560524,0.00004291471,0.000007959678,0.00007011927,0.001952305,0.00005295182,0.003286198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005875595,"threshold_uncertainty_score":0.001965582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02981085611734128,"score_gpt":0.3242527494744014,"score_spread":0.2944418933570601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}