{"id":"W2082295776","doi":"10.1016/j.cell.2015.01.052","title":"SnapShot: Genetics of ALS and FTD","year":2015,"lang":"nl","type":"article","venue":"Cell","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Medical Research Council; Alzheimer Society; Wellcome Trust","keywords":"Amyotrophic lateral sclerosis; Frontotemporal dementia; Biology; Snapshot (computer storage); C9orf72; Neuroscience; Dementia; TARDBP; Genetics; Disease; Pathology; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004044191,0.0001546697,0.0003623698,0.00006910525,0.00002562992,0.00001930817,0.0001516857,0.0001750147,0.001882527],"category_scores_gemma":[0.0001099913,0.0001278319,0.00004984708,0.0001578769,0.0002831255,0.00003711066,0.0002114106,0.0002383728,0.0006793969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006551093,"about_ca_system_score_gemma":0.0002221551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001215622,"about_ca_topic_score_gemma":0.000003406822,"domain_scores_codex":[0.9984088,0.00009823884,0.0003211347,0.0002626725,0.0005194659,0.0003897141],"domain_scores_gemma":[0.9986415,0.00007235023,0.00008988057,0.0004011419,0.0002355544,0.0005596069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006571351,0.0009709024,0.09181104,0.001886319,0.0002140727,0.0002115604,0.004624509,0.00006850377,0.6451076,0.000119538,0.2453448,0.008984062],"study_design_scores_gemma":[0.01658884,0.006185044,0.3716213,0.0009810043,0.0006314607,0.00006204423,0.001818823,0.006293649,0.3899426,0.001262678,0.2036056,0.00100702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9401101,0.01875721,0.00001651489,0.0007664947,0.0002291213,0.0003230823,0.00001679251,0.000008154624,0.03977253],"genre_scores_gemma":[0.9802832,0.003167085,0.0004163696,0.0001494347,0.0003004018,0.000003656095,0.00001762774,0.00002701786,0.01563522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2798103,"threshold_uncertainty_score":0.9990299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07652180804196351,"score_gpt":0.3180006885169214,"score_spread":0.2414788804749579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}