{"id":"W2082417169","doi":"10.4161/auto.7.9.16435","title":"Bacterial toxins can inhibit host cell autophagy through cAMP generation","year":2011,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Autophagy; Biology; Phagosome; Cell biology; Effector; Innate immune system; Immune system; Microbiology; ATG16L1; Autophagosome; Phagocytosis; Biochemistry; Immunology; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001434615,0.0002471035,0.0002865859,0.000179094,0.0001956066,0.0003078182,0.0001392472,0.0002769191,0.001082479],"category_scores_gemma":[0.0002108469,0.0001009573,0.0002354129,0.0001206496,0.0003289742,0.0001545724,0.0002502054,0.0006057866,0.0002465622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000349005,"about_ca_system_score_gemma":0.0002943189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007469089,"about_ca_topic_score_gemma":0.001213867,"domain_scores_codex":[0.999882,0.00003102021,0.000009300295,0.00001155927,0.00003222492,0.0000339212],"domain_scores_gemma":[0.9998621,0.0000527402,0.0000289884,0.00001519329,0.00001392633,0.00002711355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003156512,0.00004078381,0.0001450014,0.000099476,0.000006143404,0.00005979057,0.00001855941,0.00009961631,0.9970853,0.0002428792,0.000117062,0.001769688],"study_design_scores_gemma":[0.00003033135,0.0006267587,0.002481859,0.00001625726,0.00001285055,0.000162732,0.00002259895,0.0006481353,0.9923041,0.0001792668,0.003510501,0.000004550771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.975713,0.01477073,0.002801608,0.0006424204,0.0001347631,0.00004882569,0.0003471778,0.0001663712,0.005375082],"genre_scores_gemma":[0.9929329,0.00319708,0.001598573,0.0001239224,0.00002927182,0.00003350044,0.0003067594,0.00001322747,0.001764788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001082479,"threshold_uncertainty_score":0.00362128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04094732253423385,"score_gpt":0.260946281532988,"score_spread":0.2199989589987542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}