{"id":"W2082444360","doi":"10.1016/j.molonc.2013.09.003","title":"Secretome and degradome profiling shows that Kallikrein‐related peptidases 4, 5, 6, and 7 induce TGFβ‐1 signaling in ovarian cancer cells","year":2013,"lang":"en","type":"article","venue":"Molecular Oncology","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Cancer Council Queensland; National Health and Medical Research Council; Australian Research Council; Deutscher Akademischer Austauschdienst; Medical Research Council; Michael Smith Health Research BC; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Kallikrein; Biology; Transforming growth factor; Ovarian cancer; Cell growth; Proteases; Cell adhesion; Cell; Cell biology; Chemistry; Molecular biology; Cancer; Biochemistry; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009502357,0.0002569773,0.0002455921,0.0005855876,0.0001971027,0.0003138476,0.00006494705,0.000176878,0.0009000041],"category_scores_gemma":[0.0001124248,0.0001012216,0.0004125109,0.0005587568,0.000102223,0.0002452759,0.0002682676,0.000275854,0.0002469721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001430438,"about_ca_system_score_gemma":0.0001595354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004344686,"about_ca_topic_score_gemma":0.000514327,"domain_scores_codex":[0.9998944,0.000007215149,0.00001005831,0.00002652442,0.00004023466,0.00002162551],"domain_scores_gemma":[0.9999155,0.000009365011,0.00003174818,0.000008148546,0.00001769806,0.00001761431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001804814,0.00001386409,0.003881533,0.00005290597,0.00002012703,0.0001041114,0.00003359286,0.00006377242,0.9926893,0.00003961748,0.00006564435,0.002854994],"study_design_scores_gemma":[0.0000138134,0.0003972458,0.3232979,0.00001926916,0.0001297502,0.002003382,0.0002446423,0.002293745,0.6661177,0.0002482025,0.00520752,0.00002676232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935123,0.001174336,0.001726849,0.00006201979,0.00001392758,0.00001750006,0.002568818,0.00002913734,0.0008950375],"genre_scores_gemma":[0.9856988,0.00170763,0.003604979,0.00009314232,0.00001308496,0.0000499643,0.006646388,0.0000192557,0.002166915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009000041,"threshold_uncertainty_score":0.003010809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02061208854722459,"score_gpt":0.2812004570003709,"score_spread":0.2605883684531464,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}