{"id":"W2082448471","doi":"10.4161/cc.4.1.1401","title":"Crosstalk between p53 and FOXO Transcription Factors","year":2004,"lang":"en","type":"article","venue":"Cell Cycle","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"","keywords":"Crosstalk; Biology; Transcription factor; Forkhead Transcription Factors; Downregulation and upregulation; Transcription (linguistics); Acetylation; Cell cycle checkpoint; Cell biology; Cancer research; Phosphorylation; Cell cycle; Gene; Genetics; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003597025,0.0003213161,0.0002031509,0.0004651563,0.0003333744,0.0004633276,0.0001882282,0.0002480839,0.001737225],"category_scores_gemma":[0.0003528119,0.0001161734,0.0002193948,0.0002513253,0.0004015147,0.0004305083,0.0005094597,0.0003296819,0.0003058092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004893953,"about_ca_system_score_gemma":0.000336235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003927406,"about_ca_topic_score_gemma":0.0009903659,"domain_scores_codex":[0.9996791,0.00007439986,0.0000120873,0.00007111672,0.0000672987,0.00009607338],"domain_scores_gemma":[0.999778,0.00005257477,0.00004427661,0.00001648392,0.0000364484,0.00007212332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008881508,0.0000931819,0.007423656,0.0002136697,0.00004318188,0.001188401,0.0001718568,0.0007208499,0.9353467,0.005906035,0.0009119381,0.04709248],"study_design_scores_gemma":[0.0001912474,0.001641127,0.08532274,0.00008618963,0.0001444221,0.003063608,0.0006415168,0.004113762,0.8255171,0.01665968,0.06256323,0.00005545546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9266448,0.03675886,0.01596236,0.002840457,0.0003701488,0.00004986912,0.0003261996,0.0002581804,0.01678904],"genre_scores_gemma":[0.9833336,0.009430723,0.002431676,0.000246188,0.0001217283,0.00002060833,0.0001604465,0.00001324562,0.004241785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001737225,"threshold_uncertainty_score":0.005811632,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01007022231572784,"score_gpt":0.2221235424414359,"score_spread":0.2120533201257081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}