{"id":"W2082448471","doi":"10.4161/cc.4.1.1401","title":"Crosstalk between p53 and FOXO Transcription Factors","year":2004,"lang":"en","type":"article","venue":"Cell Cycle","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"","keywords":"Crosstalk; Biology; Transcription factor; Forkhead Transcription Factors; Downregulation and upregulation; Transcription (linguistics); Acetylation; Cell cycle checkpoint; Cell biology; Cancer research; Phosphorylation; Cell cycle; Gene; Genetics; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004636209,0.0001175103,0.00008726075,0.00002869832,0.0000864699,0.00003156064,0.00006393136,0.0001278842,0.00001865661],"category_scores_gemma":[0.000004913271,0.0001175946,0.00005830037,0.00004530912,0.00007353146,0.000009394115,0.00001199695,0.00005467809,0.00001135952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001661172,"about_ca_system_score_gemma":0.00001930521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004548442,"about_ca_topic_score_gemma":0.00002526737,"domain_scores_codex":[0.9993736,0.00001300549,0.0001260386,0.0002422638,0.00008767569,0.0001574426],"domain_scores_gemma":[0.9997033,0.000002898681,0.00003176216,0.0001571568,0.00002425467,0.00008065978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001278222,0.00002582533,0.01117416,0.00001606827,0.00000966974,4.00571e-7,0.0001653971,0.0001647797,0.9878443,0.00007163158,0.00003884142,0.0004761152],"study_design_scores_gemma":[0.0008658443,0.0001364079,0.1750586,0.00000525406,0.00001838104,0.000001517926,0.00006193007,0.000004445372,0.8139745,0.0005429601,0.009163924,0.0001661783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910645,0.000295527,0.007477038,0.00006568453,0.0000950705,0.0001211742,0.00002874727,0.00002633995,0.0008258509],"genre_scores_gemma":[0.9990819,0.00003503451,0.000295752,0.00003596042,0.00008811301,0.000003685113,0.0002456177,0.00001899033,0.0001949133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1738698,"threshold_uncertainty_score":0.4795367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01007022231572784,"score_gpt":0.2221235424414359,"score_spread":0.2120533201257081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}