{"id":"W2082449232","doi":"10.1002/mc.20617","title":"The effect of <i>c‐myc</i> on stem cell fate influences skin tumor phenotype","year":2010,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kimberly-Clark (Canada)","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute; National Institutes of Health","keywords":"Biology; Phenotype; Carcinogenesis; Stem cell; Hair follicle; Multipotent Stem Cell; Cell fate determination; Cancer research; Embryonic stem cell; Cellular differentiation; Sebaceous gland; Cell biology; Progenitor cell; Endocrinology; Genetics; Cancer; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004354375,0.0002770516,0.0002581112,0.00004482435,0.000204652,0.00002772367,0.0004486228,0.0001211512,0.000003292016],"category_scores_gemma":[0.00008779175,0.0001908174,0.0002323124,0.0001525816,0.0002178303,0.000002007897,0.0001603599,0.0001457159,0.000019353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007668498,"about_ca_system_score_gemma":0.00005384746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003431377,"about_ca_topic_score_gemma":0.00002764025,"domain_scores_codex":[0.9984609,0.0002073155,0.000274858,0.0004187315,0.0002872966,0.0003508664],"domain_scores_gemma":[0.9988278,0.00009622684,0.0001465579,0.0007315664,0.0001131189,0.00008468667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001379136,0.00001930319,0.008528008,0.00004217921,0.00007525802,0.00001532272,0.00004253562,0.0001449484,0.9880604,0.0000321347,0.0001379709,0.002764067],"study_design_scores_gemma":[0.0004085259,0.0007596795,0.003814713,0.000009839837,0.00006274181,0.000004379287,0.00003456184,0.00001145852,0.9901653,0.000008656475,0.004512698,0.0002074621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959121,0.002188619,0.0001306352,0.00004868019,0.0003099574,0.0002930425,0.00002143172,0.00001682351,0.001078709],"genre_scores_gemma":[0.9993613,0.00003854778,0.00008085628,0.000179716,0.0001049531,0.00006232566,0.00001021113,0.00004448749,0.000117597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004713295,"threshold_uncertainty_score":0.7781307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004836010232440165,"score_gpt":0.2156606268412093,"score_spread":0.2108246166087691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}