{"id":"W2082573663","doi":"10.5731/pdajpst.2014.01012","title":"Need for New Technologies for Detection of Adventitious Agents in Vaccines and Other Biological Products","year":2014,"lang":"en","type":"review","venue":"PDA Journal of Pharmaceutical Science and Technology","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi Pasteur; U.S. Food and Drug Administration; Sanofi","keywords":"Risk analysis (engineering); Computer science; Rotavirus vaccine; Biochemical engineering; Preclinical testing; Biotechnology; Rotavirus; Business; Virology; Medicine; Virus; Biology; Engineering; Medical physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003211185,0.001001391,0.002251206,0.005124298,0.0003423463,0.002038782,0.00115409,0.002623116,0.004048166],"category_scores_gemma":[0.003019228,0.000566421,0.001240361,0.002705818,0.001444754,0.004051574,0.0009186735,0.003808662,0.00253194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009765937,"about_ca_system_score_gemma":0.002194325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001822134,"about_ca_topic_score_gemma":0.001753354,"domain_scores_codex":[0.9986564,0.0002868976,0.0001459002,0.0001868559,0.0006446721,0.0000791921],"domain_scores_gemma":[0.9957317,0.002486113,0.0004842533,0.0001388488,0.001025416,0.0001336288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004726019,0.0001505362,0.0008981132,0.02176564,0.0001111528,0.0003618159,0.0001515813,0.0003845583,0.005042342,0.008263288,0.01369348,0.9491302],"study_design_scores_gemma":[0.00001452575,0.0002226173,0.002372703,0.007444965,0.0001536535,0.00297552,0.0003210615,0.0001909444,0.003339523,0.005336458,0.9775627,0.00006531126],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002598974,0.9952188,0.001109027,0.00153276,0.0003152427,0.00001472898,0.00003146581,0.00001865392,0.001499421],"genre_scores_gemma":[0.001712063,0.9944214,0.002192053,0.0005555952,0.0003440312,0.00001682512,0.00004375722,0.000004000514,0.0007101927],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005124298,"threshold_uncertainty_score":0.01698256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1722862198424877,"score_gpt":0.4749830442074569,"score_spread":0.3026968243649691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}