{"id":"W2082733262","doi":"10.1515/hmbci.2011.007","title":"Assessment of steroidogenic pathways that do not require testosterone as intermediate","year":2011,"lang":"en","type":"article","venue":"Hormone Molecular Biology and Clinical Investigation","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Aromatase; Testosterone (patch); Dihydrotestosterone; Aromatization; Androstenedione; Reductase; Hydroxysteroid dehydrogenase; Chemistry; Estrogen; Steroid; Enzyme; Endocrinology; Internal medicine; Estrone; Dehydrogenase; Biochemistry; Biology; Androgen; Hormone; Cancer; Medicine; Catalysis; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006629444,0.0006125899,0.0004660813,0.003928268,0.0003618989,0.0008615395,0.0004425384,0.0004010799,0.00516739],"category_scores_gemma":[0.0007730481,0.0001540026,0.0005247436,0.003233978,0.0003536776,0.0007152911,0.0004560274,0.000403962,0.001657677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002811497,"about_ca_system_score_gemma":0.0004275691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006325211,"about_ca_topic_score_gemma":0.001013126,"domain_scores_codex":[0.9995345,0.00008414724,0.00007015019,0.00008869312,0.0001692716,0.00005323239],"domain_scores_gemma":[0.9992684,0.0002453996,0.0001255342,0.00005606958,0.0002215337,0.00008304743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001623717,0.0002999203,0.05570731,0.006347176,0.0002307578,0.003035872,0.0006062764,0.0003881947,0.7579313,0.002830953,0.001060155,0.1699383],"study_design_scores_gemma":[0.000101403,0.00267472,0.3721206,0.0007753776,0.0009624382,0.01378183,0.002338646,0.001156354,0.4170865,0.005099139,0.1838058,0.00009713258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6861168,0.1910385,0.04439905,0.0003890037,0.0002695478,0.0005088137,0.01236131,0.0006189835,0.06429804],"genre_scores_gemma":[0.8350614,0.09147717,0.04151082,0.0005638623,0.0001393019,0.0006253702,0.01414348,0.0001768189,0.01630183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00516739,"threshold_uncertainty_score":0.01728666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04414612639254015,"score_gpt":0.3317657938705662,"score_spread":0.287619667478026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}