{"id":"W2082749530","doi":"10.1016/j.clinbiochem.2009.02.014","title":"The (mis) use of bone resorption markers in the context of bisphosphonate exposure, dental surgery and osteonecrosis of the jaw","year":2009,"lang":"en","type":"review","venue":"Clinical Biochemistry","topic":"Bone health and treatments","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; McMaster University; Hamilton Regional Laboratory Medicine Program","funders":"","keywords":"Osteonecrosis of the jaw; Medicine; Dentistry; Context (archaeology); Bone resorption; Bisphosphonate; Resorption; Bisphosphonate-associated osteonecrosis of the jaw; Bone Density Conservation Agents; Jaw bone; Surgery; Osteoporosis; Bone density; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001643258,0.000253211,0.00167218,0.0000324078,0.00005273768,0.000008896411,0.0001775827,0.000508396,0.000006047539],"category_scores_gemma":[0.002086735,0.000116107,0.0008349777,0.0002990929,0.000724119,0.00001810626,0.0000618909,0.0005574218,0.000001218009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004535613,"about_ca_system_score_gemma":0.0004693899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004448338,"about_ca_topic_score_gemma":0.00008636107,"domain_scores_codex":[0.996684,0.0003536337,0.002083929,0.0003194584,0.0003394848,0.0002195145],"domain_scores_gemma":[0.9932135,0.004431251,0.001322472,0.0008364128,0.00008945356,0.0001068909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005538946,0.0004936957,0.03068159,0.007661558,0.0001846803,0.00001337255,0.00001941148,3.346309e-9,0.0000369445,0.000003168587,0.001580882,0.9587708],"study_design_scores_gemma":[0.007345205,0.001332827,0.2362111,0.1014605,0.005893852,0.0004519878,0.000792814,0.000002674712,0.008354213,0.000043124,0.63733,0.0007816961],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2290616,0.7696812,6.560436e-8,0.0002029941,0.0001364067,0.0007184175,0.0001210016,0.000004071727,0.00007422068],"genre_scores_gemma":[0.2035174,0.796004,0.00001392458,0.0001534324,0.000008888454,0.00002522803,0.00006377196,0.0000139444,0.0001994448],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9579891,"threshold_uncertainty_score":0.4734705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09551130646647206,"score_gpt":0.3854665598622948,"score_spread":0.2899552533958228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}