{"id":"W2082756994","doi":"10.1182/blood-2010-06-291237","title":"Functional roles of aspartate residues of the proton-coupled folate transporter (PCFT-SLC46A1); a D156Y mutation causing hereditary folate malabsorption","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"National Cancer Institute","keywords":"Mutation; Folic acid; Genetics; Transporter; Malabsorption; Methylenetetrahydrofolate reductase; Medicine; Biology; Chemistry; Biochemistry; Internal medicine; Gene; Allele","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001195424,0.0005241802,0.0002779234,0.0002432853,0.0001468235,0.000203502,0.0001658771,0.0006046544,0.0009735916],"category_scores_gemma":[0.0003135887,0.0001370231,0.0002171592,0.0001549202,0.0004828396,0.0001883084,0.0002333807,0.0003188793,0.0002328666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002470126,"about_ca_system_score_gemma":0.00013749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006256999,"about_ca_topic_score_gemma":0.0004578035,"domain_scores_codex":[0.9998674,0.00002165382,0.00002544246,0.00004350121,0.00002818238,0.00001392912],"domain_scores_gemma":[0.9998131,0.0000621155,0.00006167957,0.000009968382,0.00001035053,0.0000426671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006251424,0.00004389934,0.01382197,0.00007073918,0.00001727906,0.009230481,0.0001146519,0.0002820383,0.9725592,0.0001467069,0.00004026252,0.003047593],"study_design_scores_gemma":[0.0001090482,0.0008611127,0.1279445,0.00003815877,0.0001017993,0.05374462,0.00031395,0.003031832,0.8105462,0.0003850927,0.002881805,0.00004177521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998992,0.0002732661,0.0003133801,0.0000314264,0.000006621633,0.000003585325,0.0001402105,0.000009167347,0.0002302291],"genre_scores_gemma":[0.9991047,0.0001355762,0.0004634734,0.00001312781,0.00000263364,0.000002411296,0.00007631262,0.000003261327,0.0001985146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009735916,"threshold_uncertainty_score":0.003256977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01757059894289258,"score_gpt":0.2619058766662548,"score_spread":0.2443352777233622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}