{"id":"W2082780252","doi":"10.4161/hv.28549","title":"Effects in the use of a genetically engineered strain of<i>Lactococcus lactis</i>delivering in situ IL-10 as a therapy to treat low-grade colon inflammation","year":2014,"lang":"en","type":"article","venue":"Human Vaccines & Immunotherapeutics","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Lactococcus lactis; Genetically engineered; Strain (injury); Genetically modified organism; In situ; Inflammation; Recombinant DNA; Microbiology; Medicine; Biology; Immunology; Bacteria; Chemistry; Internal medicine; Genetics; Lactic acid; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002277617,0.0004731947,0.0004421169,0.0002042947,0.0001298153,0.0004347285,0.0002417923,0.0004608044,0.0007861778],"category_scores_gemma":[0.0001638164,0.0001200357,0.0003643217,0.000153798,0.0003262481,0.0002089996,0.0001798801,0.001008043,0.0002313813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002234507,"about_ca_system_score_gemma":0.0002504701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007831973,"about_ca_topic_score_gemma":0.0007483934,"domain_scores_codex":[0.9997486,0.0000482118,0.00002986814,0.00005430346,0.00005293001,0.000065946],"domain_scores_gemma":[0.9997957,0.00004078489,0.00006972719,0.00002332192,0.00001458017,0.00005586336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004089615,0.0002396105,0.00006621124,0.00003475256,0.000005881655,0.00003851783,0.00001157012,0.0000470736,0.9981729,0.00002964956,0.00002848891,0.0009164439],"study_design_scores_gemma":[0.00005411678,0.004585098,0.001036814,0.000006350204,0.00002608651,0.0001229796,0.00002725554,0.0004079816,0.9925098,0.00001697323,0.001201449,0.000005148166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957647,0.001145686,0.001628298,0.0002009168,0.00012523,0.00005511162,0.0002588256,0.000116937,0.0007041725],"genre_scores_gemma":[0.9930511,0.0009127564,0.003380498,0.0001503596,0.00002977011,0.0000687983,0.0004460205,0.00003712622,0.001923744],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007861778,"threshold_uncertainty_score":0.002630055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02128920782259308,"score_gpt":0.2771812836365809,"score_spread":0.2558920758139878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}