{"id":"W2082868177","doi":"10.1002/mds.23714","title":"Milestones in Parkinson's disease therapeutics","year":2011,"lang":"en","type":"review","venue":"Movement Disorders","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":193,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Pramipexole; Levodopa; Parkinson's disease; Rasagiline; Selegiline; Ropinirole; Medicine; Rotigotine; Deep brain stimulation; Amantadine; Dopamine; Dyskinesia; Psychology; Dopaminergic; Neuroscience; Pharmacology; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000647226,0.0005267647,0.001212563,0.0002206368,0.00004449766,0.00001412339,0.0001729948,0.0001864892,0.0003148671],"category_scores_gemma":[0.00001398724,0.0003678122,0.0005485381,0.0002805551,0.0000888604,0.00003296498,0.00007648091,0.0003087616,0.0001393441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009012035,"about_ca_system_score_gemma":0.0001252638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007555376,"about_ca_topic_score_gemma":0.00006347219,"domain_scores_codex":[0.99821,0.00009280486,0.0004696305,0.0005870003,0.0002112634,0.0004293346],"domain_scores_gemma":[0.9990932,0.00004595499,0.0001548496,0.0004982362,0.00001292863,0.0001947681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007249296,0.001782922,0.009052494,0.003822954,0.0002518538,0.0001294863,0.00002736543,1.778814e-7,2.508441e-8,0.00035604,0.0008222871,0.9836819],"study_design_scores_gemma":[0.0009835933,0.0002541776,0.003776988,0.001915589,0.001192282,9.654109e-8,0.00001407615,0.000002370172,4.266687e-8,0.02274156,0.9688036,0.0003155696],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001197126,0.9939267,0.000005427793,0.0004935288,0.0001490956,0.001856589,0.0000398874,0.00006042259,0.00334861],"genre_scores_gemma":[0.0001373816,0.9907332,0.00003168549,0.00746545,0.00002418506,0.0005308624,0.0001684366,0.00007494171,0.0008338298],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9833663,"threshold_uncertainty_score":0.9998774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07177917005893486,"score_gpt":0.3313862286410196,"score_spread":0.2596070585820847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}