{"id":"W2082944527","doi":"10.1074/jbc.m409234200","title":"Proteolysis of Non-phosphorylated and Phosphorylated Tau by Thrombin","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Proteolysis; Phosphorylation; Thrombin; Chemistry; Biochemistry; Cell biology; Biology; Medicine; Enzyme; Internal medicine; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001652344,0.0001204895,0.0002161584,0.0000126432,0.00003153349,0.000009637951,0.0001204746,0.0002471094,0.00005782394],"category_scores_gemma":[0.0001234311,0.00009028015,0.00008852324,0.00009667484,0.0001278781,0.000005503102,0.00004531829,0.000145678,8.092781e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001489243,"about_ca_system_score_gemma":0.00004703008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003134681,"about_ca_topic_score_gemma":9.849185e-8,"domain_scores_codex":[0.9992214,0.00001607534,0.0003702683,0.0001753253,0.00009900485,0.0001178668],"domain_scores_gemma":[0.9992495,0.000004316391,0.0003657464,0.0001192026,0.0001767683,0.00008448088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001562525,0.0001324438,0.0011172,0.0000220518,0.00005921436,0.000002486815,0.00001822656,0.00001382333,0.9975938,0.000001355531,0.0004505494,0.0004325577],"study_design_scores_gemma":[0.0007846956,0.0003340156,0.002286722,0.00002529674,0.00001715657,0.0001014023,0.00004580443,0.000002459637,0.9950008,0.00006625395,0.001228256,0.0001070896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997856,0.001173907,0.0005198798,0.0002274163,0.00004784528,0.00006415721,0.0000117175,0.000004456346,0.00009465059],"genre_scores_gemma":[0.9982125,0.0009868968,0.0004260432,0.00006811185,0.0000971293,0.00000221852,0.00006552626,0.000007725297,0.0001339203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002592991,"threshold_uncertainty_score":0.3681518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006822124498161618,"score_gpt":0.2247882483630929,"score_spread":0.2179661238649313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}