{"id":"W2082959106","doi":"10.1021/ac5042439","title":"Investigation of the Utility of Complementary Electrochemical Detection Techniques to Examine the in Vitro Affinity of Bacterial Flagellins for a Toll-Like Receptor 5 Biosensor","year":2015,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Defence Research and Development Canada; The Scarborough Hospital; Royal Military College of Canada; University of Toronto","funders":"Defence Research and Development Canada","keywords":"Biosensor; Chemistry; Dielectric spectroscopy; Electrochemistry; TLR5; Nanotechnology; Analytical Chemistry (journal); Toll-like receptor; Electrode; Chromatography; Receptor; Materials science; Biochemistry; Innate immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008084757,0.0007057422,0.0004329244,0.0002248181,0.0001806341,0.0004025729,0.0006789642,0.0009288923,0.0006547615],"category_scores_gemma":[0.001442341,0.0003273948,0.0003470913,0.0001926809,0.0001965219,0.0003402561,0.0003251359,0.0006978828,0.0003854425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002483591,"about_ca_system_score_gemma":0.0001882196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005653867,"about_ca_topic_score_gemma":0.001112362,"domain_scores_codex":[0.9992322,0.0002159051,0.0000535873,0.0001208151,0.0002836185,0.00009384803],"domain_scores_gemma":[0.9992415,0.0003856212,0.00007944227,0.00005067976,0.0001976465,0.00004519112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001826522,0.00001716981,0.00004640538,0.00003555697,0.000005378713,0.00002025896,0.00001041914,0.00003412255,0.9991278,0.00002293512,0.000009146428,0.0006525673],"study_design_scores_gemma":[0.000003638721,0.0002469143,0.0004685677,0.000004616033,0.00001602953,0.0001647936,0.00002628079,0.00156074,0.9970468,0.00001748327,0.0004384418,0.000005699594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9316419,0.004450521,0.06117219,0.00035993,0.0002200655,0.0001029628,0.0001794978,0.0001445489,0.001728414],"genre_scores_gemma":[0.9409978,0.00236646,0.05397734,0.0002522054,0.00003762589,0.0000934129,0.0002548782,0.00001987419,0.002000459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009288923,"threshold_uncertainty_score":0.00427568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02779622909243354,"score_gpt":0.2364553504574529,"score_spread":0.2086591213650194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}